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GENE：LARP4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LARP4
FullNmae La ribonucleoprotein 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24320
EnsembleID ENSG00000161813
Uniprot Q71RC2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LARP4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LARP4 GO:0003723,GO:0003730,GO:0003730,GO:0005515,GO:0005829,GO:0005829,GO:0006412,GO:0007010,GO:0008143,GO:0010494,GO:0010608,GO:0016020,GO:0022604,GO:0045727,GO:0045727

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP LARP4 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 LARP4 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LARP4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 LARP4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 LARP4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 LARP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LARP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 LARP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LARP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LARP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LARP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LARP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 LARP4 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000BE495 LARP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000521626 LARP4 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
BHLHE40 LARP4 25348397 N/A physical interaction ComPPI
CRX LARP4 25348397 N/A physical interaction ComPPI
NPM1 LARP4 24234451 25348397 26496610 30021884 association,physical association anti tag coimmunoprecipitation,cross-linking study,physical interaction ComPPI,IntAct
TOMM22 LARP4 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
KEAP1 LARP4 25348397 N/A physical interaction ComPPI
RACK1 LARP4 25348397 N/A physical interaction ComPPI
RPL10 LARP4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JUN LARP4 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL3 LARP4 25348397 N/A physical interaction ComPPI
NTRK1 LARP4 25348397 N/A physical interaction ComPPI
YBX1 LARP4 24234451 25348397 25497084 association anti bait coimmunoprecipitation ComPPI,IntAct
AKAP1 LARP4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPL LARP4 25348397 N/A physical interaction ComPPI
EGFR LARP4 25348397 N/A physical interaction ComPPI
COPS6 LARP4 25348397 N/A physical interaction ComPPI
ELAVL1 LARP4 25348397 N/A physical interaction ComPPI
ESR1 LARP4 21182205 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
TOMM20 LARP4 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TARDBP LARP4 25348397 N/A physical interaction ComPPI
MPG LARP4 25348397 N/A physical interaction ComPPI
MYO1C LARP4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF126 LARP4 25348397 N/A physical interaction ComPPI
MNDA LARP4 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
MGST3 LARP4 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SIRT7 LARP4 25348397 N/A physical interaction ComPPI
KSR1 LARP4 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
APP LARP4 25348397 N/A physical interaction ComPPI
G3BP1 LARP4 25348397 N/A physical interaction ComPPI
LIN28B LARP4 25348397 N/A physical interaction ComPPI
LRRK2 LARP4 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
LARP4 LIN28A 25348397 N/A physical interaction ComPPI
LARP4 NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
LARP4 LARP4 12220179 30476227 association pull down,biochemical TheBiogrid
ZPBP2 LARP4 25450970 30476227 physical association affinity chromatography technology,protein complementation assay TheBiogrid
PABPC1 LARP4 21098120 27898060 N/A N/A OmniPath

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