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GENE：TXN2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TXN2
FullNmae thioredoxin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17772
EnsembleID ENSG00000100348
Uniprot Q99757

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TXN2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TXN2 GO:0001666,GO:0005515,GO:0005730,GO:0005739,GO:0005739,GO:0005759,GO:0006979,GO:0008113,GO:0009410,GO:0009725,GO:0009749,GO:0014070,GO:0015035,GO:0030425,GO:0031669,GO:0033743,GO:0043025,GO:0044877,GO:0045454,GO:0048678

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TXN2 hsa:25828 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
TXN2 hsa:25828 path:hsa05012 Parkinson disease - Homo sapiens (human)
TXN2 hsa:25828 path:hsa05132 Salmonella infection - Homo sapiens (human)
TXN2 hsa:25828 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TXN2 RELA 14527995 23180781 physical association anti tag coimmunoprecipitation InnateDB
AP2B1 TXN2 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 TXN2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 TXN2 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TXN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TXN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TXN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TXN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TXN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TXN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TXN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX3 TXN2 17956589 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D TXN2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C3AC1 TXN2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000048BA36 TXN2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 TXN2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001B341F TXN2 25416803 28356525 mrna cleavage,inhibition array technology,western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
TXN2 GLRX 25361965 interaction type N/A PTMCode2
GLRX TXN2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BCAS2 TXN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT18 TXN2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TTC32 TXN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC197 TXN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM21 TXN2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 SSNA1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 ZBTB14 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 RPIA 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 KRT40 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 TIFA 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 REEP6 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 MRFAP1L1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 UCHL5 25348397 N/A physical interaction ComPPI
TXN2 UBR5 25348397 N/A physical interaction ComPPI
TXN2 MRPL23 25348397 N/A physical interaction ComPPI
TXN2 RPL8 25348397 N/A physical interaction ComPPI
TXN2 RPL9 25348397 N/A physical interaction ComPPI
TXN2 SNRNP70 25348397 N/A physical interaction ComPPI
TXN2 PTBP3 25348397 N/A physical interaction ComPPI
TXN2 GOLIM4 25348397 N/A physical interaction ComPPI
TXN2 HSPA1L 25348397 N/A physical interaction ComPPI
TXN2 TOMM22 25348397 N/A physical interaction ComPPI
TXN2 RPS16 25348397 N/A physical interaction ComPPI
TXN2 ILF3 25348397 N/A physical interaction ComPPI
TXN2 ILF2 25348397 N/A physical interaction ComPPI
TXN2 SPTBN1 25348397 N/A physical interaction ComPPI
TXN2 TPM4 25348397 N/A physical interaction ComPPI
TXN2 VCP 25348397 N/A physical interaction ComPPI
TXN2 MLH1 20706999 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TXN2 GPRASP2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 ALDOB 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TXN2 SHARPIN 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TXN2 VIM 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TXN2 RABAC1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TXN2 THAP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TXN2 NR3C1 25348397 N/A physical interaction ComPPI
TXN2 RELA 25348397 N/A physical interaction ComPPI
TXN2 AP2B1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 DCTD 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 MAGEA11 25348397 N/A physical interaction ComPPI
TXN2 VPS52 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 TRIP6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 PSME3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 STUB1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 MAPRE2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 MAPRE3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 MTUS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 KCTD7 25348397 N/A physical interaction ComPPI
TXN2 RABGEF1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 AGTRAP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 SCYL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 PPCDC 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 ODAD1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 RBM45 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 FAM9B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN2 MAP3K5 25348397 N/A physical interaction ComPPI
TXN2 MOV10 25348397 N/A physical interaction ComPPI
TXN2 ANXA6 25348397 N/A physical interaction ComPPI
TXN2 FAM98B 25348397 N/A physical interaction ComPPI
TXN2 SOD1 25348397 N/A physical interaction ComPPI
TXN2 TXN 25348397 N/A physical interaction ComPPI
TXN2 WDR12 25348397 N/A physical interaction ComPPI
TXN2 TXNIP 25348397 N/A physical interaction ComPPI
TXN2 DDIT3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 ABI3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 MDFI 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 UQCC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 SAT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 STN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 TFIP11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 CDCA4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 HAUS8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 HAUS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 SYCE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 MIPOL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 CGGBP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 GTPBP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 MRFAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 TMOD4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 LCN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 MAGEA4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 CHMP1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 PPP1R16B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 CIB4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 MAGEB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 CEP70 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 POMC 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 ZMYND12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 FHL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 DMBX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 SPTA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 PEX19 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 KRT27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 ETHE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 GOLGA6L9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN2 BHLHB9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RPS3A TXN2 24234451 30021884 physical association cross-linking study IntAct
LY6E TXN2 16272220 23414292 27898060 N/A N/A OmniPath

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