Gene Information gene info

GENE:CCNL2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CCNL2
FullNmae cyclin L2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20570
EnsembleID ENSG00000221978
Uniprot Q96S94

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CCNL2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CCNL2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CCNL2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CCNL2 GO:0000307,GO:0000307,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0006357,GO:0016538,GO:0016607,GO:0042981,GO:0043231,GO:0043484,GO:0043484,GO:0046605,GO:0051726

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 CCNL2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA CCNL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CCNL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CCNL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CCNL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 CCNL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CCNL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CCNL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 CCNL2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000195F5B CCNL2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 CCNL2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 CCNL2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 CCNL2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 CCNL2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 CCNL2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF CCNL2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 CCNL2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F CCNL2 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DYRK1A CCNL2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CCNL2 DYRK1A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
YES1 CCNL2 25348397 N/A physical interaction ComPPI
ZBTB43 CCNL2 25348397 N/A physical interaction ComPPI
PRKACB CCNL2 25348397 N/A physical interaction ComPPI
NF2 CCNL2 25348397 N/A physical interaction ComPPI
LYN CCNL2 25348397 N/A physical interaction ComPPI
PRKCA CCNL2 25348397 N/A physical interaction ComPPI
SRC CCNL2 25348397 N/A physical interaction ComPPI
RRAS CCNL2 25348397 N/A physical interaction ComPPI
GNAQ CCNL2 25348397 N/A physical interaction ComPPI
SNX1 CCNL2 25348397 N/A physical interaction ComPPI
SNX6 CCNL2 25348397 N/A physical interaction ComPPI
DIAPH1 CCNL2 25348397 N/A physical interaction ComPPI
CNTN1 CCNL2 25348397 N/A physical interaction ComPPI
PROCR CCNL2 25348397 N/A physical interaction ComPPI
PTPRG CCNL2 25348397 N/A physical interaction ComPPI
RUNDC3A CCNL2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SRSF2 CCNL2 25348397 N/A in vivo ComPPI
CSNK2A2 CCNL2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
AP1B1 CCNL2 25348397 N/A physical interaction ComPPI
JAK3 CCNL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK7 CCNL2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POLR2A CCNL2 25348397 N/A physical interaction,in vivo ComPPI
PYGB CCNL2 25348397 N/A physical interaction ComPPI
FYN CCNL2 25348397 N/A physical interaction ComPPI
GNA11 CCNL2 25348397 N/A physical interaction ComPPI
CSTF3 CCNL2 25348397 N/A physical interaction ComPPI
CCNL2 CDK11B 25348397 N/A physical interaction,in vivo ComPPI
CCNL2 SRSF7 25348397 N/A in vivo ComPPI
CCNL2 DYRK1A 25348397 N/A physical interaction,in vitro,in vivo ComPPI
CCNL2 CDK11A 25348397 N/A physical interaction ComPPI
CCNL2 JMJD6 25348397 N/A physical interaction ComPPI
CCNL2 SMPDL3B 25348397 N/A physical interaction ComPPI
CCNL2 ABCF2 25348397 N/A physical interaction ComPPI
CCNL2 IRF2BP2 25348397 N/A physical interaction ComPPI
CCNL2 ULBP3 25348397 N/A physical interaction ComPPI
CCNL2 IREB2 25348397 N/A physical interaction ComPPI
CCNL2 EHD1 25348397 N/A physical interaction ComPPI
CCNL2 GNB4 25348397 N/A physical interaction ComPPI
CCNL2 GAP43 25348397 N/A physical interaction ComPPI
CCNL2 IRF2BP1 25348397 N/A physical interaction ComPPI
CCNL2 CCNY 25348397 N/A physical interaction ComPPI
CCNL2 NSDHL 25348397 N/A physical interaction ComPPI
CCNL2 DCAF1 25348397 N/A physical interaction ComPPI
CCNL2 SAMHD1 25348397 N/A physical interaction ComPPI
CCNL2 HDAC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNL2 KIF22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNL2 CENPQ 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNL2 OCC1 25348397 N/A physical interaction ComPPI
CCNL2 RNPS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GNAZ CCNL2 25348397 N/A physical interaction ComPPI
CBR3 CCNL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUFM CCNL2 24234451 30021884 physical association cross-linking study IntAct
DYRK1A CCNL2 14623875 18452278 18669648 19413330 19651622 19664994 19664995 20068231 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009AFBCE CCNL2 27087310 direct interaction,inhibition N/A NPInter

Visualization