GENE:MED13L
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | MED13L |
FullNmae | mediator complex subunit 13L |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:22962 |
EnsembleID | ENSG00000123066 |
Uniprot | Q71F56 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
MED13L | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
MED13L | GO:0003712,GO:0006357,GO:0016592 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
MED13L | hsa:23389 | path:hsa04919 | Thyroid hormone signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | MED13L | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ESR1 | MED13L | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | MED13L | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA1 | MED13L | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | MED13L | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
HIF1A | MED13L | 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
FOXP3 | MED13L | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TAL1 | MED13L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000272039 | MED13L | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS0000122ED0 | MED13L | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000DDD35 | MED13L | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS00003D5391 | MED13L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000035CC3E | MED13L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00005FDE70 | MED13L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000183BED | MED13L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000000B1C9 | MED13L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00004407DC | MED13L | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000B0E50 | MED13L | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
TP53BP1 | MED13L | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
MED21 | MED13L | 25348397 | N/A | physical interaction | ComPPI |
FBXW7 | MED13L | 25348397 | N/A | physical interaction | ComPPI |
HIF1A | MED13L | 23746844 24234451 25348397 | association | pull down,physical interaction | ComPPI,IntAct |
MED1 | MED13L | 25348397 | N/A | physical interaction | ComPPI |
SYNCRIP | MED13L | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MED9 | MED13L | 14638676 15175163 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MED23 | MED13L | 25348397 | N/A | physical interaction | ComPPI |
MED28 | MED13L | 25348397 | N/A | physical interaction | ComPPI |
MED12 | MED13L | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CDK8 | MED13L | 23602568 24234451 25348397 26496610 29568061 | association | anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification,proximity-dependent biotin identification | ComPPI,IntAct |
MED13 | MED13L | 14525934 15175163 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
TRIM25 | MED13L | 25348397 | N/A | physical interaction | ComPPI |
SORT1 | MED13L | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CDK19 | MED13L | 15175163 23602568 24234451 25348397 | association,physical association | physical interaction,ion exchange chromatography,tandem affinity purification | ComPPI,IntAct |
MED19 | MED13L | 15175163 21729782 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MED13L | MED10 | 14576168 15175163 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MED13L | CCNC | 25348397 | N/A | physical interaction | ComPPI |
MED13L | MED4 | 25348397 | N/A | physical interaction | ComPPI |
MED18 | MED13L | 25348397 | N/A | physical interaction | ComPPI |
IMMT | MED13L | 24234451 30021884 | physical association | cross-linking study | IntAct |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00009B4818 | MED13L | 27087310 | direct interaction,inhibition | N/A | NPInter |