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GENE：ATP2B4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP2B4
FullNmae ATPase plasma membrane Ca2+ transporting 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:817
EnsembleID ENSG00000058668
Uniprot P23634

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP2B4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP2B4 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATP2B4 GO:0003407,GO:0005388,GO:0005388,GO:0005388,GO:0005515,GO:0005516,GO:0005524,GO:0005886,GO:0005886,GO:0005886,GO:0005901,GO:0006357,GO:0006874,GO:0006874,GO:0006874,GO:0007283,GO:0010629,GO:0010751,GO:0014832,GO:0015085,GO:0016020,GO:0016020,GO:0016323,GO:0016525,GO:0016887,GO:0017080,GO:0019901,GO:0021766,GO:0030018,GO:0030165,GO:0030315,GO:0030317,GO:0030346,GO:0030346,GO:0030346,GO:0032991,GO:0033138,GO:0034220,GO:0036126,GO:0036487,GO:0043231,GO:0043537,GO:0045019,GO:0045121,GO:0046872,GO:0048787,GO:0050998,GO:0051001,GO:0051480,GO:0051599,GO:0070588,GO:0070885,GO:0070885,GO:0071872,GO:0097110,GO:0097228,GO:0097553,GO:0098703,GO:0098736,GO:0098978,GO:0140199,GO:0150104,GO:1900082,GO:1901660,GO:1902083,GO:1902305,GO:1902548,GO:1902806,GO:1903078,GO:1903243,GO:1903249,GO:1903779,GO:1905145,GO:2000481

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP2B4 hsa:493 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
ATP2B4 hsa:493 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
ATP2B4 hsa:493 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
ATP2B4 hsa:493 path:hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)
ATP2B4 hsa:493 path:hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human)
ATP2B4 hsa:493 path:hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human)
ATP2B4 hsa:493 path:hsa04970 Salivary secretion - Homo sapiens (human)
ATP2B4 hsa:493 path:hsa04972 Pancreatic secretion - Homo sapiens (human)
ATP2B4 hsa:493 path:hsa04978 Mineral absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ERBIN ATP2B4 15123239 23180781 physical association peptide array InnateDB
NOS3 ATP2B4 20211863 23180781 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 ATP2B4 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ATP2B4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ATP2B4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ATP2B4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ATP2B4 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 ATP2B4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 ATP2B4 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ATP2B4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 ATP2B4 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D ATP2B4 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00000BE495 ATP2B4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002FC5B0 ATP2B4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 ATP2B4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 ATP2B4 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS00004719AB ATP2B4 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS00001BCAC5 ATP2B4 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F ATP2B4 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 ATP2B4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 ATP2B4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000035CC3E ATP2B4 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RASSF1 ATP2B4 25361965 interaction type N/A PTMCode2
ATP2B4 RASSF1 25361965 interaction type N/A PTMCode2
DLG4 ATP2B4 25361965 interaction type N/A PTMCode2
ATP2B4 DLG4 25361965 interaction type N/A PTMCode2
YWHAE ATP2B4 25361965 interaction type N/A PTMCode2
ATP2B4 YWHAE 25361965 interaction type N/A PTMCode2
CD22 ATP2B4 25361965 interaction type N/A PTMCode2
ATP2B4 CD22 25361965 interaction type N/A PTMCode2
ATP2B4 DLG3 25361965 interaction type N/A PTMCode2
DLG3 ATP2B4 25361965 interaction type N/A PTMCode2
ATP2B4 CASK 25361965 interaction type N/A PTMCode2
CASK ATP2B4 25361965 interaction type N/A PTMCode2
ATP2B4 PPP3CA 25361965 interaction type N/A PTMCode2
PPP3CA ATP2B4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LGALS3 ATP2B4 25348397 N/A physical interaction ComPPI
AGTR1 ATP2B4 25348397 N/A physical interaction ComPPI
CALM1 ATP2B4 25348397 N/A x-ray crystallography,physical interaction ComPPI
NMUR2 ATP2B4 25348397 N/A physical interaction ComPPI
LGALS9C ATP2B4 25348397 N/A physical interaction ComPPI
DLG4 ATP2B4 11274188 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ERBIN ATP2B4 25348397 N/A physical interaction ComPPI
SRC ATP2B4 12540962 14525934 25348397 9182531 N/A experimental interaction detection,in vivo ComPPI,HPRD
CANX ATP2B4 25348397 N/A physical interaction ComPPI
CDH1 ATP2B4 25348397 N/A physical interaction ComPPI
KCNA5 ATP2B4 25348397 N/A physical interaction ComPPI
DLG2 ATP2B4 11274188 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LILRB4 ATP2B4 25348397 N/A physical interaction ComPPI
CFTR ATP2B4 25348397 N/A physical interaction ComPPI
CD47 ATP2B4 23219802 24234451 25348397 association cross-linking study ComPPI,IntAct
CASK ATP2B4 12511555 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
AQP1 ATP2B4 23219802 24234451 25348397 association cross-linking study ComPPI,IntAct
DLG1 ATP2B4 11274188 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ATP1A1 ATP2B4 25348397 N/A physical interaction ComPPI
ADRB2 ATP2B4 25348397 N/A physical interaction ComPPI
EGFR ATP2B4 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
YWHAE ATP2B4 16126729 24234451 25348397 association coimmunoprecipitation ComPPI,IntAct
CDK7 ATP2B4 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RASSF1 ATP2B4 14525934 15145946 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
DLG3 ATP2B4 11274188 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
GPC1 ATP2B4 25348397 N/A physical interaction ComPPI
LGALS8 ATP2B4 25348397 N/A physical interaction ComPPI
ATP2B4 PPP3CA 14525934 15955804 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
ATP2B4 CD22 14525934 15133509 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ATP2B4 NOS1 11591728 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
ATP2B4 BSG 25348397 N/A physical interaction ComPPI
ATP2B4 TAS2R7 25348397 N/A physical interaction ComPPI
ATP2B4 EDA2R 25348397 N/A physical interaction ComPPI
ATP2B4 HSD17B6 25348397 N/A physical interaction ComPPI
ATP2B4 LGALS9 25348397 N/A physical interaction ComPPI
ATP2B4 SLC39A4 25348397 N/A physical interaction ComPPI
ATP2B4 LYPD3 25348397 N/A physical interaction ComPPI
ATP2B4 DLK1 25348397 N/A physical interaction ComPPI
ATP2B4 WBP1 25348397 N/A physical interaction ComPPI
ATP2B4 PTGER3 25348397 N/A physical interaction ComPPI
ATP2B4 TMEM52B 25348397 N/A physical interaction ComPPI
ATP2B4 ATP9A 25348397 N/A physical interaction ComPPI
ATP2B4 HM13 25348397 N/A physical interaction ComPPI
ATP2B4 ATP5PF 25348397 N/A physical interaction ComPPI
ATP2B4 CLGN 25348397 N/A physical interaction ComPPI
ATP2B4 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP2B4 CTDSPL 25348397 N/A physical interaction ComPPI
ATP2B4 ATP2B2 25348397 N/A physical interaction ComPPI
ATP2B4 RXYLT1 25348397 N/A physical interaction ComPPI
ATP2B4 LPAR1 25348397 N/A physical interaction ComPPI
ATP2B4 FPR2 25348397 N/A physical interaction ComPPI
ATP2B4 IPPK 25348397 N/A physical interaction ComPPI
ATP2B4 FAM174A 25348397 N/A physical interaction ComPPI
ATP2B4 C3AR1 25348397 N/A physical interaction ComPPI
ATP2B4 CYP2B6 25348397 N/A physical interaction ComPPI
ATP2B4 PCDHGB1 25348397 N/A physical interaction ComPPI
ATP2B4 APLNR 25348397 N/A physical interaction ComPPI
ATP2B4 HTR3A 25348397 N/A physical interaction ComPPI
ATP2B4 VAC14 25348397 N/A physical interaction ComPPI
ATP2B4 TRIM25 25348397 N/A physical interaction ComPPI
ATP2B4 CALCA 17689535 24234451 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
ATP2B4 STIM1 22246182 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation ComPPI,IntAct,OmniPath
ATP2B4 SLC4A1 23219802 24234451 25348397 association cross-linking study ComPPI,IntAct
ATP2B4 FLOT1 23219802 24234451 25348397 association cross-linking study ComPPI,IntAct
ATP2B4 FLOT2 23219802 24234451 25348397 association cross-linking study ComPPI,IntAct
ATP2B4 SLC2A1 23219802 24234451 25348397 association cross-linking study ComPPI,IntAct
ATP2B4 SLC29A1 23219802 24234451 25348397 association cross-linking study ComPPI,IntAct
ATP2B4 STOM 23219802 24234451 25348397 association cross-linking study ComPPI,IntAct
ATP2B4 SLC14A1 23219802 24234451 25348397 association cross-linking study ComPPI,IntAct
COX5B ATP2B4 24234451 30021884 physical association cross-linking study IntAct
SRC ATP2B4 12540962 27898060 9182531 N/A N/A OmniPath
PTK2 ATP2B4 12540962 25847233 27898060 N/A N/A OmniPath
SYK ATP2B4 12540962 27898060 9182531 N/A N/A OmniPath
DLG1 ATP2B4 11274188 27898060 N/A N/A OmniPath
ERBIN ATP2B4 15123239 27898060 N/A N/A OmniPath
DLG4 ATP2B4 11274188 27898060 N/A N/A OmniPath
DLG3 ATP2B4 11274188 27898060 N/A N/A OmniPath
DLG2 ATP2B4 11274188 17384233 27898060 N/A N/A OmniPath

Visualization










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