Gene Information gene info

  1. Home

GENE：ORC6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ORC6
FullNmae origin recognition complex subunit 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17151
EnsembleID ENSG00000091651
Uniprot Q9Y5N6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ORC6 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ORC6 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ORC6 GO:0000808,GO:0001650,GO:0003677,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005664,GO:0005664,GO:0005829,GO:0006270,GO:0006270,GO:0016020

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ORC6 hsa:23594 path:hsa04110 Cell cycle - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDC45 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
MCM2 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
MCM3 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
MCM4 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
MCM6 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
MCM7 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
ORC1 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
ORC2 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
ORC3 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
ORC4 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
ORC5 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
ORC6 CDC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
ORC6 MCM5 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDK2 ORC6 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 26192618 7575488 interaction type N/A ACSN
CDC7 ORC6 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 26192618 7575488 interaction type N/A ACSN
DBF4 ORC6 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 26192618 7575488 interaction type N/A ACSN
RPA1 ORC6 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258 26192618 interaction type N/A ACSN
RPA2 ORC6 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258 26192618 interaction type N/A ACSN
RPA3 ORC6 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258 26192618 interaction type N/A ACSN
HUS1 ORC6 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD1 ORC6 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 ORC6 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
CDK1 ORC6 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 26192618 7575488 interaction type N/A ACSN
ATRIP ORC6 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATR ORC6 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 ORC6 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CLSPN ORC6 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
TIPIN ORC6 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
APP ORC6 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ORC6 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA ORC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ORC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ORC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ORC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ORC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ORC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 ORC6 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00005651EE ORC6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003380CC ORC6 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C ORC6 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000156390 ORC6 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 ORC6 20371350 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEF5F ORC6 20371350 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 ORC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E ORC6 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000003ABC4 ORC6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 ORC6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E ORC6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 ORC6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 ORC6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD ORC6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D ORC6 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004E008F ORC6 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 ORC6 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C ORC6 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004818BD ORC6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000045ED38 ORC6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000027F5F3 ORC6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C0099 ORC6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000547F6A ORC6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000021202F ORC6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 ORC6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075CC78 ORC6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075D814 ORC6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001012BC ORC6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003AD2AA ORC6 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 ORC6 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SNW1 ORC6 25348397 N/A physical interaction ComPPI
CDC5L ORC6 25348397 N/A physical interaction ComPPI
MCM5 ORC6 12614612 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MCM6 ORC6 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
MCM2 ORC6 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
LHX4 ORC6 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ORC6 SPAG5 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ORC6 ORC2 11323433 14525934 16549788 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
ORC6 CDC6 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
ORC6 ORC3 11323433 14525934 15232106 17716973 24234451 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,protein array,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
ORC6 MCM4 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
ORC6 ORC4 14525934 15232106 18234858 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro,bimolecular fluorescence complementation ComPPI,HPRD,IntAct
ORC6 CDC7 12614612 14525934 15232106 24234451 25348397 N/A two hybrid,experimental interaction detection,protein array,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
ORC6 MCM7 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
ORC6 ORC5 18234858 24234451 25348397 N/A physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ORC6 DBF4 25348397 N/A physical interaction ComPPI
ORC6 CDC45 25348397 N/A physical interaction ComPPI
ORC6 TERF2 25348397 N/A physical interaction ComPPI
ORC6 HMGA1 18234858 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ORC6 XRCC5 25348397 N/A physical interaction ComPPI
ORC6 XRCC6 25348397 N/A physical interaction ComPPI
ORC6 APP 25348397 N/A physical interaction ComPPI
ORC6 LRWD1 25348397 N/A physical interaction ComPPI
ORC6 SFPQ 25348397 N/A physical interaction ComPPI
ORC6 PSPC1 25348397 N/A physical interaction ComPPI
ORC6 BICD2 25348397 N/A physical interaction ComPPI
ORC6 ACTR10 25348397 N/A physical interaction ComPPI
ORC6 CREB1 25348397 N/A physical interaction ComPPI
ORC6 DCTN6 25348397 N/A physical interaction ComPPI
ORC6 PPIL4 25348397 N/A physical interaction ComPPI
ORC6 CDT1 22581055 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
RPA1 ORC6 25348397 N/A physical interaction ComPPI
ORC6 SU(VAR)205 25348397 N/A physical interaction ComPPI
ORC6 ORC6 14525934 15232106 N/A experimental interaction detection HPRD

Visualization










  Return