Gene Information gene info

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GENE：PPOX

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPOX
FullNmae protoporphyrinogen oxidase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9280
EnsembleID ENSG00000143224
Uniprot P50336

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPOX pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PPOX autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PPOX GO:0004729,GO:0004729,GO:0005743,GO:0005758,GO:0006779,GO:0006782,GO:0006783,GO:0006783,GO:0031966,GO:0050660

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PPOX hsa:5498 path:hsa00860 Porphyrin metabolism - Homo sapiens (human)
PPOX hsa:5498 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PPOX hsa:5498 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PPOX 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 PPOX 18191920 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PPOX 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A PPOX 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 PPOX 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF PPOX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PPOX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PPOX 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 PPOX 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
COPS5 PPOX 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLAUR PPOX 25348397 N/A physical interaction ComPPI
HAP1 PPOX 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
IMMT PPOX 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARSA PPOX 25348397 N/A physical interaction ComPPI
HNRNPD PPOX 25348397 N/A physical interaction ComPPI
NDUFS7 PPOX 25348397 N/A physical interaction ComPPI
PPOX NDUFA10 25348397 N/A physical interaction ComPPI
PPOX NANOG 25348397 N/A physical interaction ComPPI
PPOX POU5F1 25348397 N/A physical interaction ComPPI
PPOX COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PPOX EPB41L3 24497494 27898060 N/A N/A OmniPath

Visualization










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