GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
LRRC8E |
FullNmae |
leucine rich repeat containing 8 VRAC subunit E |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:26272 |
EnsembleID |
ENSG00000171017 |
Uniprot |
Q6NSJ5 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
LRRC8E |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
LRRC8E |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
LRRC8E |
GO:0005225,GO:0005225,GO:0005515,GO:0005737,GO:0005765,GO:0005789,GO:0005886,GO:0005886,GO:0005886,GO:0006884,GO:0007165,GO:0015810,GO:0034702,GO:0071470,GO:0098656,GO:0140361 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
TFAP2C |
LRRC8E |
20629094
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
CEBPA |
LRRC8E |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
LRRC8E |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
LRRC8E |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS000003ABC4 |
LRRC8E |
19088304
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
PTGIR |
LRRC8E |
25348397
|
N/A |
physical interaction |
ComPPI |
GPSM2 |
LRRC8E |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
LGALS8 |
LRRC8E |
25348397
|
N/A |
physical interaction |
ComPPI |
TRIM25 |
LRRC8E |
25348397
|
N/A |
physical interaction |
ComPPI |
ESR2 |
LRRC8E |
24234451
25348397
25604459
|
association |
tandem affinity purification |
ComPPI,IntAct |
LNX2 |
LRRC8E |
25348397
|
N/A |
physical interaction |
ComPPI |
TBC1D4 |
LRRC8E |
25348397
|
N/A |
physical interaction |
ComPPI |
TRMT6 |
LRRC8E |
25348397
|
N/A |
physical interaction |
ComPPI |
DMD |
LRRC8E |
25348397
|
N/A |
physical interaction |
ComPPI |
NXF1 |
LRRC8E |
25348397
|
N/A |
physical interaction |
ComPPI |
MOV10 |
LRRC8E |
25348397
|
N/A |
physical interaction |
ComPPI |
PPME1 |
LRRC8E |
25348397
|
N/A |
physical interaction |
ComPPI |
DDHD2 |
LRRC8E |
25348397
|
N/A |
physical interaction |
ComPPI |
LRRC8E |
PGAM5 |
24234451
30021884
|
physical association |
cross-linking study |
IntAct |
Visualization