GENE：TIPARP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TIPARP |
| FullNmae | TCDD inducible poly(ADP-ribose) polymerase |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:23696 |
| EnsembleID | ENSG00000163659 |
| Uniprot | Q7Z3E1 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TIPARP | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TIPARP | GO:0000987,GO:0001570,GO:0001822,GO:0003950,GO:0003950,GO:0005634,GO:0005634,GO:0006807,GO:0008209,GO:0008210,GO:0008585,GO:0009791,GO:0010629,GO:0016779,GO:0030097,GO:0045732,GO:0046872,GO:0048008,GO:0048705,GO:0048745,GO:0060021,GO:0060325,GO:0071407,GO:0140803,GO:1904612,GO:1990404,GO:1990404 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TIPARP | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | TIPARP | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | TIPARP | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | TIPARP | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | TIPARP | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | TIPARP | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | TIPARP | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | TIPARP | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | TIPARP | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | TIPARP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TIPARP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TIPARP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | TIPARP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TIPARP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TIPARP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TIPARP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | TIPARP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000170CF4 | TIPARP | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS000003ABC4 | TIPARP | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001E0AEA | TIPARP | 22815788 25416803 | mrna cleavage,inhibition | array technology,quantitative reverse transcription pcr | TarBase |
| URS000042619A | TIPARP | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000153377 | TIPARP | 22815788 25416803 | mrna cleavage,inhibition | array technology,quantitative reverse transcription pcr | TarBase |
| URS000000E601 | TIPARP | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000052EA98 | TIPARP | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ATM | TIPARP | 25361965 | interaction type | N/A | PTMCode2 |
| TIPARP | ATM | 25361965 | interaction type | N/A | PTMCode2 |
| XRCC1 | TIPARP | 25361965 | interaction type | N/A | PTMCode2 |
| TIPARP | XRCC1 | 25361965 | interaction type | N/A | PTMCode2 |
| TP53 | TIPARP | 25361965 | interaction type | N/A | PTMCode2 |
| TIPARP | TP53 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| XRN2 | TIPARP | 14525934 15231747 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| ATM | TIPARP | 11238919 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| RPL11 | TIPARP | 24234451 30021884 | physical association | cross-linking study | IntAct |