GENE:CNOT6L
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CNOT6L |
| FullNmae | CCR4-NOT transcription complex subunit 6 like |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:18042 |
| EnsembleID | ENSG00000138767 |
| Uniprot | Q96LI5 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CNOT6L | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CNOT6L | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CNOT6L | GO:0000289,GO:0000289,GO:0000289,GO:0004535,GO:0004535,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006397,GO:0008284,GO:0010606,GO:0030014,GO:0030014,GO:0030014,GO:0031047,GO:0046872 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CNOT6L | hsa:246175 | path:hsa03018 | RNA degradation - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | CNOT6L | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CNOT6L | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | CNOT6L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CNOT6L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CNOT6L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | CNOT6L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CNOT6L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CNOT6L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CNOT6L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000600E6 | CNOT6L | 20371350 21572407 23446348 23592263 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS000021D7C8 | CNOT6L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001EFBE3 | CNOT6L | 23591815 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS00002E1509 | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000016914 | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037D7E5 | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003883FE | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040828B | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000025EABA | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006F90B | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039E1E1 | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | CNOT6L | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000020579D | CNOT6L | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000015A0D9 | CNOT6L | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | CNOT6L | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000060AABB | CNOT6L | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00006097A6 | CNOT6L | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002367FA | CNOT6L | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F1B8C | CNOT6L | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E6EFA | CNOT6L | 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002578DA | CNOT6L | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000049FAE8 | CNOT6L | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | CNOT6L | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000427B68 | CNOT6L | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A4ABF | CNOT6L | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AFAD1 | CNOT6L | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BEA7 | CNOT6L | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000486E0B | CNOT6L | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000338542 | CNOT6L | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076E54 | CNOT6L | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003575B | CNOT6L | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | CNOT6L | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | CNOT6L | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CNOT6L | CNOT8 | 25361965 | interaction type | N/A | PTMCode2 |
| CNOT8 | CNOT6L | 25361965 | interaction type | N/A | PTMCode2 |
| CNOT6L | CHAF1A | 25361965 | interaction type | N/A | PTMCode2 |
| CHAF1A | CNOT6L | 25361965 | interaction type | N/A | PTMCode2 |
| CNOT6L | CNOT7 | 25361965 | interaction type | N/A | PTMCode2 |
| CNOT7 | CNOT6L | 25361965 | interaction type | N/A | PTMCode2 |
| CNOT2 | CNOT6L | 25361965 | interaction type | N/A | PTMCode2 |
| CNOT6L | CNOT2 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| VASN | CNOT6L | 25348397 | N/A | physical interaction | ComPPI |
| NANOS2 | CNOT6L | 25348397 | N/A | physical interaction | ComPPI |
| MMP7 | CNOT6L | 25348397 | N/A | physical interaction | ComPPI |
| TOB1 | CNOT6L | 18377426 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction,tandem affinity purification | ComPPI,IntAct |
| GADD45B | CNOT6L | 25348397 | N/A | physical interaction | ComPPI |
| CHAF1A | CNOT6L | 25348397 | N/A | physical interaction | ComPPI |
| ZFP36 | CNOT6L | 25348397 | N/A | physical interaction | ComPPI |
| BTG2 | CNOT6L | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NFKB1 | CNOT6L | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| CHAF1B | CNOT6L | 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CNOT7 | CNOT6L | 17452450 21984185 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,inference by socio-affinity scoring | ComPPI,IntAct |
| CNOT8 | CNOT6L | 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TNKS1BP1 | CNOT6L | 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| CNOT1 | CNOT6L | 17452450 21984185 22977175 24234451 25348397 26496610 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CNOT2 | CNOT6L | 17452450 24234451 25348397 26496610 | association,physical association | anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| CNOT3 | CNOT6L | 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CNOT6 | CNOT6L | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| AGO2 | CNOT6L | 21981923 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RAB29 | CNOT6L | 25348397 | N/A | physical interaction | ComPPI |
| LZTR1 | CNOT6L | 25348397 | N/A | physical interaction | ComPPI |
| GPBP1L1 | CNOT6L | 25348397 | N/A | physical interaction | ComPPI |
| CNOT9 | CNOT6L | 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TNRC6B | CNOT6L | 21981923 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CNOT10 | CNOT6L | 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| CNOT6L | ZSCAN1 | 25348397 | N/A | physical interaction | ComPPI |
| CNOT6L | TNRC6A | 21981923 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CNOT6L | CAPZA2 | 25348397 | N/A | physical interaction | ComPPI |
| CNOT6L | TNRC6C | 21981923 21984185 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
| CNOT6L | RC3H1 | 25348397 | N/A | physical interaction | ComPPI |
| CNOT6L | CNOT11 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| CNOT6L | RIBC1 | 25348397 | N/A | physical interaction | ComPPI |
| TEX13A | CNOT6L | 25348397 | N/A | physical interaction | ComPPI |
