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GENE：NFE2L1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NFE2L1
FullNmae NFE2 like bZIP transcription factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7781
EnsembleID ENSG00000082641
Uniprot Q14494

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NFE2L1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NFE2L1 GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005789,GO:0005829,GO:0006357,GO:0006357,GO:0006783,GO:0008203,GO:0008289,GO:0009653,GO:0042802

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR NFE2L1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 NFE2L1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 NFE2L1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 NFE2L1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A NFE2L1 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 NFE2L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NFE2L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NFE2L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NFE2L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NFE2L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NFE2L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NFE2L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 NFE2L1 20587593 trascriptional regulation,stimulation inferred by curator TFlink
ESR1 NFE2L1 21486948 trascriptional regulation,stimulation inferred by curator TFlink
MEF2A NFE2L1 18222924 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 NFE2L1 20587593 trascriptional regulation,stimulation inferred by curator TFlink
RELA NFE2L1 20587593 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000148B91 NFE2L1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E NFE2L1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE NFE2L1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D NFE2L1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002367FA NFE2L1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000157026 NFE2L1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000239117 NFE2L1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004505E4 NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000472A9B NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC NFE2L1 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005CC20C NFE2L1 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000010BD8D NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000013DD8 NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 NFE2L1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002971AB NFE2L1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000060AABB NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000009A9A2 NFE2L1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000366551 NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000001EB3 NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000EED18 NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027352D NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002C7B2B NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D1FC NFE2L1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002AAD6B NFE2L1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001F5B39 NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003758F0 NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002198F3 NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F1B8C NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122F23 NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000023F008 NFE2L1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075B538 NFE2L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D15B NFE2L1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002C02E4 NFE2L1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000358C16 NFE2L1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039D790 NFE2L1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GSK3B NFE2L1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
ATF4 NFE2L1 11025215 14525934 20102225 24234451 25348397 27898060 N/A two hybrid,experimental interaction detection,peptide array,in vitro,two hybrid ComPPI,HPRD,IntAct,OmniPath
KEAP1 NFE2L1 16687406 21262351 21988832 24127568 24234451 25348397 27898060 physical association two hybrid,physical interaction ComPPI,IntAct,OmniPath
JUNB NFE2L1 14525934 25348397 9872330 N/A experimental interaction detection,in vitro ComPPI,HPRD
BATF NFE2L1 20102225 24234451 25348397 N/A peptide array ComPPI,IntAct
CREBZF NFE2L1 20102225 24234451 25348397 N/A peptide array,physical interaction ComPPI,IntAct
FBXW7 NFE2L1 21953459 23623971 25348397 27898060 N/A physical interaction ComPPI,OmniPath
JUN NFE2L1 14525934 25348397 9872330 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HCFC1 NFE2L1 25348397 N/A physical interaction ComPPI
MAFB NFE2L1 20102225 24234451 25348397 N/A peptide array ComPPI,IntAct
JUND NFE2L1 14525934 25348397 9872330 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAFG NFE2L1 14525934 20102225 23661758 24234451 25348397 27898060 8932385 9150357 9421508 N/A experimental interaction detection,peptide array,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
MAFF NFE2L1 14525934 25348397 8932385 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GSK3B NFE2L1 25348397 N/A physical interaction ComPPI
BTRC NFE2L1 25348397 N/A physical interaction ComPPI
NFE2 NFE2L1 20102225 24234451 25348397 N/A peptide array ComPPI,IntAct
MAFK NFE2L1 12805554 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NFE2L3 NFE2L1 25348397 N/A physical interaction ComPPI
BACH2 NFE2L1 25348397 N/A physical interaction ComPPI
PHF12 NFE2L1 25348397 N/A physical interaction ComPPI
ATF7 NFE2L1 20102225 24234451 25348397 N/A peptide array ComPPI,IntAct
CAPN1 NFE2L1 12358155 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FBXW11 NFE2L1 25348397 N/A physical interaction ComPPI
RUSC2 NFE2L1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NFE2L1 CD6 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NFE2L1 WDFY3 25348397 N/A physical interaction ComPPI
NFE2L1 C8ORF33 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NFE2L1 BRD9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NFE2L1 GATAD1 25348397 N/A physical interaction ComPPI
NFE2L1 USP15 25348397 N/A physical interaction ComPPI
NFE2L1 TULP3 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
NFE2L1 FOS 20102225 24234451 25348397 N/A peptide array ComPPI,IntAct
NFE2L1 NFE2L1 20102225 24234451 N/A peptide array IntAct
MAPK14 NFE2L1 15308669 27898060 N/A N/A OmniPath
GSK3B NFE2L1 23623971 27898060 inhibition N/A OmniPath

Visualization










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