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GENE：PPP2R2D

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPP2R2D
FullNmae protein phosphatase 2 regulatory subunit Bdelta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23732
EnsembleID ENSG00000175470
Uniprot Q66LE6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPP2R2D mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PPP2R2D immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PPP2R2D autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PPP2R2D GO:0000159,GO:0000159,GO:0000278,GO:0005515,GO:0005829,GO:0010458,GO:0019888,GO:0019888,GO:0051301

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PPP2R2D hsa:55844 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)
PPP2R2D hsa:55844 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)
PPP2R2D hsa:55844 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
PPP2R2D hsa:55844 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)
PPP2R2D hsa:55844 path:hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)
PPP2R2D hsa:55844 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)
PPP2R2D hsa:55844 path:hsa04530 Tight junction - Homo sapiens (human)
PPP2R2D hsa:55844 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
PPP2R2D hsa:55844 path:hsa04728 Dopaminergic synapse - Homo sapiens (human)
PPP2R2D hsa:55844 path:hsa05142 Chagas disease - Homo sapiens (human)
PPP2R2D hsa:55844 path:hsa05160 Hepatitis C - Homo sapiens (human)
PPP2R2D hsa:55844 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PPP2R2D 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PPP2R2D 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PPP2R2D 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 PPP2R2D 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PPP2R2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NF1 PPP2R2D 22539979 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 PPP2R2D 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000032BD73 PPP2R2D 25416803 27074866 mrna cleavage,inhibition experimental interaction detection,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CCDC130 PPP2R2D 25348397 N/A physical interaction ComPPI
SNAI2 PPP2R2D 25348397 N/A physical interaction ComPPI
PPP2R1A PPP2R2D 18782753 19156129 24234451 25348397 26496610 27173435 28330616 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification,proximity-dependent biotin identification,inference by socio-affinity scoring ComPPI,IntAct
TTC33 PPP2R2D 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
MCM2 PPP2R2D 25348397 N/A physical interaction ComPPI
FOXC2 PPP2R2D 25348397 N/A physical interaction ComPPI
PPP4C PPP2R2D 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
JUN PPP2R2D 25348397 N/A physical interaction ComPPI
COP1 PPP2R2D 25348397 N/A physical interaction ComPPI
CREB5 PPP2R2D 25348397 N/A physical interaction ComPPI
PPP2R5A PPP2R2D 25348397 N/A physical interaction ComPPI
PTPN5 PPP2R2D 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP2CB PPP2R2D 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IQGAP1 PPP2R2D 25348397 N/A physical interaction ComPPI
CFTR PPP2R2D 25348397 N/A physical interaction ComPPI
PPP2CA PPP2R2D 18782753 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RASA3 PPP2R2D 24234451 25348397 28330616 association pull down ComPPI,IntAct
UNG PPP2R2D 24234451 25348397 28330616 association pull down ComPPI,IntAct
TCP1 PPP2R2D 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CCT5 PPP2R2D 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CCT7 PPP2R2D 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PINX1 PPP2R2D 25348397 N/A physical interaction ComPPI
MTREX PPP2R2D 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PPP2R2A PPP2R2D 24234451 25348397 28330616 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HDAC5 PPP2R2D 25348397 N/A physical interaction ComPPI
SUPT5H PPP2R2D 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CDK16 PPP2R2D 25348397 N/A physical interaction ComPPI
BCL2L14 PPP2R2D 25348397 N/A physical interaction ComPPI
WNT3A PPP2R2D 25348397 N/A physical interaction ComPPI
CRY2 PPP2R2D 25348397 N/A physical interaction ComPPI
ECSIT PPP2R2D 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
MLH1 PPP2R2D 25348397 N/A physical interaction ComPPI
DMAP1 PPP2R2D 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATF7 PPP2R2D 25348397 N/A physical interaction ComPPI
YEATS4 PPP2R2D 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
PPP2R1B PPP2R2D 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PPP2R5D PPP2R2D 25348397 N/A physical interaction ComPPI
BAG2 PPP2R2D 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
RAB11FIP5 PPP2R2D 25348397 N/A physical interaction ComPPI
ATXN2L PPP2R2D 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
ATF2 PPP2R2D 25348397 N/A physical interaction ComPPI
GYS1 PPP2R2D 24234451 25348397 28330616 association pull down ComPPI,IntAct
TCEAL1 PPP2R2D 25348397 N/A physical interaction ComPPI
RRP1B PPP2R2D 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ULK2 PPP2R2D 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SARNP PPP2R2D 25348397 N/A physical interaction ComPPI
WDR61 PPP2R2D 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
BMP15 PPP2R2D 25348397 N/A physical interaction ComPPI
ACLY PPP2R2D 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
WNT7A PPP2R2D 25348397 N/A physical interaction ComPPI
NDUFAF1 PPP2R2D 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
RPS11 PPP2R2D 24234451 25348397 28330616 association pull down ComPPI,IntAct
CCT4 PPP2R2D 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CCT2 PPP2R2D 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CCT6A PPP2R2D 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PPP2R2D ATAD3B 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
PPP2R2D ZCCHC8 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PPP2R2D PPME1 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PPP2R2D CCT8 19156129 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP2R2D CCT3 19156129 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PPP2R2D DAPK1 20220139 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP2R2D PABIR1 25348397 N/A physical interaction ComPPI
PPP2R2D SERTAD4 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
PPP2R2D WNT10B 25348397 N/A physical interaction ComPPI
PPP2R2D AAMP 25348397 N/A physical interaction ComPPI
PPP2R2D PLEKHO2 25348397 N/A physical interaction ComPPI
PPP2R2D IER2 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
PPP2R2D PTTG1 25348397 N/A physical interaction ComPPI
PPP2R2D PTTG2 25348397 N/A physical interaction ComPPI
PPP2R2D FOXC1 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
PPP2R2D C1ORF87 25348397 N/A physical interaction ComPPI
PPP2R2D TRMT2A 25348397 N/A physical interaction ComPPI
PPP2R2D SLX4 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PPP2R2D UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PPP2R2D PHF5A 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP2R2D PPP2R2C 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP2R2D ATAD3A 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP2R2D CCAR2 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
PPP2R2D PPP2R2B 24234451 25348397 28330616 association pull down ComPPI,IntAct

Visualization










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