GENE：EHD3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | EHD3 |
| FullNmae | EH domain containing 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:3244 |
| EnsembleID | ENSG00000013016 |
| Uniprot | Q9NZN3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| EHD3 | lysosomal_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| EHD3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| EHD3 | GO:0001881,GO:0003676,GO:0005509,GO:0005515,GO:0005524,GO:0005525,GO:0005634,GO:0005737,GO:0005737,GO:0005769,GO:0005829,GO:0005886,GO:0005925,GO:0006897,GO:0010008,GO:0015031,GO:0020018,GO:0030139,GO:0032456,GO:0032456,GO:0034498,GO:0048471,GO:0051260,GO:0055038,GO:0055038,GO:0055117,GO:0060271,GO:0060271,GO:0072659,GO:0072659,GO:0086036,GO:0090160,GO:1903358,GO:1903779 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| EHD3 | hsa:30845 | path:hsa04144 | Endocytosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | EHD3 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | EHD3 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| PRDM14 | EHD3 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | EHD3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | EHD3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | EHD3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | EHD3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000058BB84 | EHD3 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000381CEC | EHD3 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D1FC | EHD3 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F74F1 | EHD3 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000023BE29 | EHD3 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | EHD3 | 19536157 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A4ABF | EHD3 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AFAD1 | EHD3 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CF056 | EHD3 | 22012620 23446348 24906430 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000027464B | EHD3 | 22012620 23446348 24906430 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B7E30 | EHD3 | 22012620 23446348 24906430 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A122A | EHD3 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004A6E26 | EHD3 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043C1C3 | EHD3 | 19536157 23824327 24906430 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000078918 | EHD3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004900F1 | EHD3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | EHD3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | EHD3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040FA88 | EHD3 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SNAP29 | EHD3 | 11423532 14525934 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| HNRNPL | EHD3 | 25348397 | N/A | physical interaction | ComPPI |
| MICALL1 | EHD3 | 19864458 24234451 25348397 27189942 | physical association | two hybrid,isothermal titration calorimetry,pull down | ComPPI,IntAct |
| RBSN | EHD3 | 15020713 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| RAB11FIP2 | EHD3 | 25348397 | N/A | physical interaction | ComPPI |
| EHD1 | EHD3 | 12121420 14525934 16251358 24234451 25348397 26226295 27898060 | colocalization,physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,fluorescence microscopy,in vivo,two hybrid prey pooling approach,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
| EHD3 | ANK2 | 20489164 24234451 25348397 | physical association | two hybrid,pull down | ComPPI,IntAct |
| EHD3 | ANKFY1 | 24234451 25348397 27189942 | physical association | two hybrid,pull down | ComPPI,IntAct |