GENE：ENC1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ENC1 |
| FullNmae | ectodermal-neural cortex 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:3345 |
| EnsembleID | ENSG00000171617 |
| Uniprot | O14682 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ENC1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ENC1 | GO:0000785,GO:0003779,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005856,GO:0007399,GO:0010499,GO:0010499,GO:0010976,GO:0016363,GO:0016567,GO:0017148,GO:0031463,GO:0031463,GO:0043025 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ENC1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | ENC1 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | ENC1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | ENC1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | ENC1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | ENC1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | ENC1 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | ENC1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | ENC1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | ENC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000F31F4 | ENC1 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | ENC1 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000017EA6A | ENC1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000192A75 | ENC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000184017 | ENC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040828B | ENC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075994C | ENC1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NUDCD3 | ENC1 | 25348397 | N/A | physical interaction | ComPPI |
| ACTB | ENC1 | 15208678 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| KEAP1 | ENC1 | 25348397 | N/A | physical interaction | ComPPI |
| HSP90AB1 | ENC1 | 22939624 24234451 25348397 | physical association | luminescence based mammalian interactome mapping | ComPPI,IntAct |
| RB1 | ENC1 | 14525934 16306221 25348397 27898060 9566959 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| NFE2L2 | ENC1 | 25348397 | N/A | physical interaction | ComPPI |
| RBX1 | ENC1 | 25348397 | N/A | physical interaction | ComPPI |
| CUL3 | ENC1 | 25348397 | N/A | physical interaction | ComPPI |
| HSP90AA1 | ENC1 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | ENC1 | 25348397 | N/A | physical interaction | ComPPI |
| SQSTM1 | ENC1 | 25348397 | N/A | physical interaction | ComPPI |
| ENC1 | NACC1 | 25348397 | N/A | physical interaction | ComPPI |
| ENC1 | SNCA | 25348397 | N/A | physical interaction | ComPPI |
| ENC1 | HSP90AA2P | 25348397 | N/A | physical interaction | ComPPI |
| ENC1 | KLHL25 | 25348397 | N/A | physical interaction | ComPPI |
| ENC1 | PLIN5 | 25348397 | N/A | physical interaction | ComPPI |
| ENC1 | TGFBR1 | 14525934 15761153 | N/A | experimental interaction detection | HPRD |
| ENC1 | NFE2L2 | 17875699 18981988 19424503 20511222 27898060 | inhibition | N/A | OmniPath |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00008BFA45 | ENC1 | 27087310 | direct interaction,inhibition | N/A | NPInter |