GENE：PNRC1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PNRC1 |
| FullNmae | proline rich nuclear receptor coactivator 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17278 |
| EnsembleID | ENSG00000146278 |
| Uniprot | Q12796 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PNRC1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PNRC1 | GO:0000184,GO:0000932,GO:0005515,GO:0005634 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GRB2 | PNRC1 | 15122321 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| EGR1 | PNRC1 | 19374776 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| RORA | PNRC1 | 15604093 23180781 | physical association | two hybrid | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PNRC1 | 10894149 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | PNRC1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | PNRC1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | PNRC1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | PNRC1 | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| YBX1 | PNRC1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | PNRC1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | PNRC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PNRC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | PNRC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PNRC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PNRC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | PNRC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PNRC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PNRC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ESRRA | PNRC1 | 10894149 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NR3C1 | PNRC1 | 10894149 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NR5A1 | PNRC1 | 10894149 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ESR1 | PNRC1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ESR2 | PNRC1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RARA | PNRC1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RARB | PNRC1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RARG | PNRC1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | PNRC1 | 18185580 23592263 23824327 25416803 | mrna cleavage,inhibition | array technology,clip | TarBase |
| URS0000122ED0 | PNRC1 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000277201 | PNRC1 | 23622248 23824327 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS00000BE495 | PNRC1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001A405B | PNRC1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000006FDD4 | PNRC1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000029EBD | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000153377 | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C11BC | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031602A | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000251D0B | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F7766 | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003ABC4 | PNRC1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039E1E1 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A4ABF | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F5FEE | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000002569A | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000308E4D | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000002CF68 | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BC299 | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000192A75 | PNRC1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000035AC91 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB14 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021D7C8 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002971AB | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000021D08 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E949 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000346991 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000070CD2 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | PNRC1 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000044FD7 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029D9F1 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075E2C3 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F0130 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043D2C1 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008AA34 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000118224 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000015188E | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CE0C6 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000042B108 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001B0D1E | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000753AD | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003380CC | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002004E0 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171020 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004A9320 | PNRC1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000009C45F | PNRC1 | 25416803 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| DDX6 | PNRC1 | 25348397 | N/A | physical interaction | ComPPI |
| RARA | PNRC1 | 17641689 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| RARB | PNRC1 | 14525934 15604093 25348397 | N/A | physical interaction,two hybrid | ComPPI,HPRD |
| DCP1A | PNRC1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MAPK8 | PNRC1 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| CRKL | PNRC1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GRB2 | PNRC1 | 14525934 15122321 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| AR | PNRC1 | 10428808 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| DCP1B | PNRC1 | 25348397 | N/A | physical interaction | ComPPI |
| HNF4A | PNRC1 | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| UPF1 | PNRC1 | 19150429 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| PNRC1 | ESR2 | 14525934 15604093 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| PNRC1 | ESRRG | 14525934 15604093 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| PNRC1 | HNF4G | 14525934 15604093 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| PNRC1 | NR5A2 | 14525934 15604093 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| PNRC1 | RORA | 14525934 15604093 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| PNRC1 | RORB | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| PNRC1 | RARG | 14525934 15604093 25348397 | N/A | physical interaction,two hybrid | ComPPI,HPRD |
| PNRC1 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| PNRC1 | UNK | 25348397 | N/A | physical interaction | ComPPI |
| PNRC1 | POLR3F | 17612402 24234451 25348397 27898060 | physical association | anti tag coimmunoprecipitation,two hybrid | ComPPI,IntAct,OmniPath |
| PNRC1 | PNRC1 | 17612402 24234451 | physical association | two hybrid | IntAct |
| NPM1 | PNRC1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| GRB2 | PNRC1 | 15122321 27898060 | N/A | N/A | OmniPath |