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GENE：PPP1R3C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPP1R3C
FullNmae protein phosphatase 1 regulatory subunit 3C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9293
EnsembleID ENSG00000119938
Uniprot Q9UQK1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPP1R3C autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PPP1R3C GO:0000164,GO:0004722,GO:0005515,GO:0005829,GO:0005977,GO:0005978,GO:0005979,GO:0008157,GO:0019903,GO:0060090,GO:2001069

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PPP1R3C hsa:5507 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
PPP1R3C hsa:5507 path:hsa04931 Insulin resistance - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PPP1R3C 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 PPP1R3C 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PPP1R3C 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 PPP1R3C 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A PPP1R3C 18971253 19828020 20888814 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
FOXA1 PPP1R3C 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PPP1R3C 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA PPP1R3C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PPP1R3C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PPP1R3C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PPP1R3C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PPP1R3C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PPP1R3C N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 PPP1R3C 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA1 PPP1R3C 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GNG5 PPP1R3C 25348397 N/A physical interaction ComPPI
SGTA PPP1R3C 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP1CC PPP1R3C 24234451 25348397 28330616 association,physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LXN PPP1R3C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1CB PPP1R3C 24234451 25348397 25416956 28330616 association,physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STBD1 PPP1R3C 25348397 N/A physical interaction ComPPI
PPP1R3C NHLRC1 25348397 N/A physical interaction ComPPI
PPP1R3C EPM2A 14532330 24234451 25348397 colocalization,physical association two hybrid,fluorescence technology,pull down,physical interaction ComPPI,IntAct
PPP1R3C PPP1CA 22321011 24234451 25348397 28330616 association,physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1R3C ELAVL1 25348397 N/A physical interaction ComPPI
PPP1R3C APP 25348397 N/A physical interaction ComPPI
PPP1R3C GYS2 25348397 N/A physical interaction ComPPI
PPP1R3C GYS1 24234451 25348397 28330616 physical association pull down,physical interaction ComPPI,IntAct
PPP1R3C TXNRD2 25348397 N/A physical interaction ComPPI
PPP1R3C LACRT 25348397 N/A physical interaction ComPPI
PPP1R3C GYG1 25348397 N/A physical interaction ComPPI
PPP1R3C EEA1 25348397 N/A physical interaction ComPPI
PPP1R3C PPP1R3D 25348397 N/A physical interaction ComPPI
PPP1R3C AASDHPPT 25348397 N/A physical interaction ComPPI
PPP1R3C LONRF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1R3C MYO6 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP1R3C LIMA1 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP1R3C TPM4 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP1R3C ACTBL2 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP1R3C PHKB 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP1R3C DBN1 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP1R3C PHKG2 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP1R3C MYO1B 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP1R3C MYO1C 24234451 25348397 28330616 association pull down ComPPI,IntAct
PRKAA1 PPP1R3C 19171932 27898060 N/A N/A OmniPath

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