Gene Information gene info

  1. Home

GENE：PTPN18

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTPN18
FullNmae protein tyrosine phosphatase non-receptor type 18
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9649
EnsembleID ENSG00000072135
Uniprot Q99952

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTPN18 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTPN18 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTPN18 GO:0001825,GO:0004725,GO:0004726,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006470,GO:0035335,GO:1901185

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 PTPN18 20690147 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 PTPN18 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PTPN18 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PTPN18 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PTPN18 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC PTPN18 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 PTPN18 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PTPN18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTPN18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PTPN18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTPN18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PTPN18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTPN18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PTPN18 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000075B0F6 PTPN18 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001CC0F4 PTPN18 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000049FAE8 PTPN18 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TEC PTPN18 22135298 phosphorylation N/A PhosphoSite
PTPN18 CSK 25361965 interaction type N/A PTMCode2
CSK PTPN18 25361965 interaction type N/A PTMCode2
PTPN18 SRC 25361965 interaction type N/A PTMCode2
SRC PTPN18 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ERBB2 PTPN18 14525934 14660651 24234451 25081058 25348397 N/A experimental interaction detection,x-ray crystallography,phosphatase assay,in vitro ComPPI,HPRD,IntAct
PTPN18 SRC 12554790 14525934 15588985 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPN18 TEC 14525934 14679216 15588985 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN18 ARHGAP5 12554790 14525934 15588985 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPN18 PSTPIP1 11971877 14525934 24234451 25348397 9265651 9422760 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
PTPN18 PSTPIP2 14525934 25348397 9804817 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN18 CSK 11158295 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
PTPN18 GRB2 21706016 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPN18 MOV10 25348397 N/A physical interaction ComPPI
PTPN18 NXF1 25348397 N/A physical interaction ComPPI
PTPN18 EGFR 24234451 24658140 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
PTPN18 AIFM1 25348397 N/A physical interaction ComPPI
PTPN18 AIP 25348397 N/A physical interaction ComPPI
PTPN18 ATP5F1A 25348397 N/A physical interaction ComPPI
PTPN18 ATXN2 25348397 N/A physical interaction ComPPI
PTPN18 BAG2 25348397 N/A physical interaction ComPPI
PTPN18 BAG5 25348397 N/A physical interaction ComPPI
PTPN18 DNAJA2 25348397 N/A physical interaction ComPPI
PTPN18 DNAJB1 25348397 N/A physical interaction ComPPI
PTPN18 DNAJC7 25348397 N/A physical interaction ComPPI
PTPN18 IRS4 25348397 N/A physical interaction ComPPI
PTPN18 MLLT11 25348397 N/A physical interaction ComPPI
PTPN18 NUP155 25348397 N/A physical interaction ComPPI
PTPN18 SDF4 25348397 N/A physical interaction ComPPI
PTPN18 STOML2 25348397 N/A physical interaction ComPPI
PTPN18 TARS2 25348397 N/A physical interaction ComPPI
PTPN18 TUBB2A 25348397 N/A physical interaction ComPPI
PTPN18 TUBB6 25348397 N/A physical interaction ComPPI
PTPN18 CBWD2 25348397 N/A physical interaction ComPPI
PTPN18 GLA 25348397 N/A physical interaction ComPPI
PTPN18 CTSB 25348397 N/A physical interaction ComPPI
PTPN18 MAIP1 25348397 N/A physical interaction ComPPI
PTPN18 STIP1 25348397 N/A physical interaction ComPPI
PTPN18 CPVL 25348397 N/A physical interaction ComPPI
PTPN18 ARL1 25348397 N/A physical interaction ComPPI
PTPN18 CDIPT 25348397 N/A physical interaction ComPPI
PTPN18 SSTR4 25348397 N/A physical interaction ComPPI
PTPN18 TMX3 25348397 N/A physical interaction ComPPI
PTPN18 RHOT1 25348397 N/A physical interaction ComPPI
PTPN18 ARF1 25348397 N/A physical interaction ComPPI
PTPN18 HAX1 25348397 N/A physical interaction ComPPI
PTPN18 NDUFS3 25348397 N/A physical interaction ComPPI
PTPN18 AATK 25348397 N/A physical interaction ComPPI
PTPN18 HNRNPL 25348397 N/A physical interaction ComPPI
PTPN18 ABL2 23322602 24234451 25348397 association pull down ComPPI,IntAct
PTPN18 SH2D1B 23322602 24234451 25348397 association pull down ComPPI,IntAct
PTPN18 BTRC 24234451 25081058 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GAB1 PTPN18 14525934 14660651 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN18 ABL1 11163214 14525934 15588985 N/A experimental interaction detection HPRD
PRKCA PTPN18 16094384 27898060 N/A N/A OmniPath
PTPN18 FYN 11158295 27898060 N/A N/A OmniPath
PTPN18 ABL1 11163214 15588985 27898060 N/A N/A OmniPath
PTPN18 ARHGAP35 12554790 27898060 N/A N/A OmniPath
PTPN18 PSTPIP1 11971877 27898060 9265651 9422760 N/A N/A OmniPath
TEC PTPN18 14679216 15588985 23322602 27898060 N/A N/A OmniPath

Visualization










  Return