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GENE：STAM

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol STAM
FullNmae signal transducing adaptor molecule
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11357
EnsembleID ENSG00000136738
Uniprot Q92783

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
STAM autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
STAM GO:0005515,GO:0005829,GO:0005829,GO:0007165,GO:0016236,GO:0031901,GO:0033565,GO:0033565,GO:0033565,GO:0033565,GO:0035091,GO:0036258,GO:0036258,GO:0043130,GO:0043231,GO:0043328,GO:0043328,GO:0044389,GO:0090148,GO:1903543,GO:1903551

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
STAM hsa:8027 path:hsa04144 Endocytosis - Homo sapiens (human)
STAM hsa:8027 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
STAM ARRB1 20505072 23180781 physical association pull down InnateDB
JAK3 STAM 23331499 9133424 stimulation N/A SignaLink
JAK2 STAM 23331499 9133424 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
STAM JAK2 20005715 interaction type N/A PSP
STAM JAK1 18988627 20005715 9133424 interaction type N/A PSP,SignaLink
STAM JAK3 10899310 18988627 20005715 interaction type N/A PSP,SignaLink
STAMBP STAM 10383417 10982817 16730941 16996268 17078930 18988627 20542890 21071413 N/A N/A SignaLink
STAM JAK2 18988627 20005715 21071413 9133424 N/A N/A SignaLink
USP8 STAM 10982817 16996268 17711858 18988627 20542890 20736164 21071413 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR STAM 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 STAM 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 STAM 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 STAM 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP73 STAM 19558638 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 STAM 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 STAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA STAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 STAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 STAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 STAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS STAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A STAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF STAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 STAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 STAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 STAM 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 STAM 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000000B1C9 STAM 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001E0AEA STAM 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000058BB84 STAM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC STAM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 STAM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 STAM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 STAM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB STAM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041E11D STAM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB STAM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 STAM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 STAM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039D790 STAM 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
STAM JAK2 25361965 interaction type N/A PTMCode2
JAK2 STAM 25361965 interaction type N/A PTMCode2
STAM JAK3 25361965 interaction type N/A PTMCode2
JAK3 STAM 25361965 interaction type N/A PTMCode2
USP8 STAM 25361965 interaction type N/A PTMCode2
STAM USP8 25361965 interaction type N/A PTMCode2
HGS STAM 25361965 interaction type N/A PTMCode2
STAM HGS 25361965 interaction type N/A PTMCode2
JAK1 STAM 25361965 interaction type N/A PTMCode2
STAM JAK1 25361965 interaction type N/A PTMCode2
CLTC STAM 25361965 interaction type N/A PTMCode2
STAM CLTC 25361965 interaction type N/A PTMCode2
STAMBP STAM 25361965 interaction type N/A PTMCode2
STAM STAMBP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LCP2 STAM 17235283 24234451 25348397 N/A peptide array ComPPI,IntAct
ZNRD2 STAM 25348397 N/A physical interaction ComPPI
PPP1CC STAM 25348397 N/A physical interaction ComPPI
ARRDC3 STAM 25348397 N/A physical interaction ComPPI
TLE3 STAM 25348397 N/A physical interaction ComPPI
TPM2 STAM 25348397 N/A physical interaction ComPPI
YWHAB STAM 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HGS STAM 14525934 16189514 19278655 24234451 25348397 9407053 physical association cosedimentation in solution,dynamic light scattering,experimental interaction detection,light scattering,molecular sieving,x-ray crystallography,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vivo ComPPI,HPRD,IntAct
SERPINH1 STAM 25348397 N/A physical interaction ComPPI
UBC STAM 12750381 16771824 17078930 19111546 20150893 20504764 21187078 23314748 24234451 25348397 26456826 26601948 27898060 N/A nuclear magnetic resonance,surface plasmon resonance,x-ray crystallography,physical interaction ComPPI,IntAct,OmniPath
NTRK1 STAM 25348397 N/A physical interaction ComPPI
JAK1 STAM 14525934 25348397 9133424 N/A experimental interaction detection,in vivo ComPPI,HPRD
SNX1 STAM 25348397 N/A physical interaction ComPPI
PIR STAM 25348397 N/A physical interaction ComPPI
PPP1CA STAM 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
STAM2 STAM 25348397 N/A physical interaction ComPPI
S100A11 STAM 25348397 N/A physical interaction ComPPI
ARRB1 STAM 25348397 N/A physical interaction ComPPI
CLTC STAM 25348397 N/A physical interaction ComPPI
UBQLN2 STAM 25348397 N/A physical interaction ComPPI
ZRANB2 STAM 25348397 N/A physical interaction ComPPI
CPLX1 STAM 25348397 N/A physical interaction ComPPI
JAK3 STAM 10899310 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JAK2 STAM 14525934 25348397 9133424 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TRIM63 STAM 25348397 N/A physical interaction ComPPI
UBQLN4 STAM 25348397 N/A physical interaction ComPPI
SNTA1 STAM 25348397 N/A physical interaction ComPPI
ASAP1 STAM 16636290 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
ITCH STAM 25348397 N/A physical interaction ComPPI
USP8 STAM 10982817 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MED28 STAM 16964398 24234451 25348397 physical association peptide array,physical interaction ComPPI,IntAct
GGA1 STAM 25348397 N/A physical interaction ComPPI
IGBP1 STAM 25348397 N/A physical interaction ComPPI
PJA1 STAM 25348397 N/A physical interaction ComPPI
STMN2 STAM 25348397 N/A physical interaction ComPPI
TIMM8A STAM 12745081 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
STAM STAMBP 10383417 10982817 12810066 14525934 15314065 16431367 16520378 16730941 16760479 17078930 20159979 24151880 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,isothermal titration calorimetry,pull down,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
STAM CXCR4 25348397 N/A physical interaction ComPPI
STAM CD79B 25348397 N/A physical interaction ComPPI
STAM SEC31A 25348397 N/A physical interaction ComPPI
STAM SORT1 25348397 N/A physical interaction ComPPI
STAM RFFL 25348397 N/A physical interaction ComPPI
STAM TRIM55 25348397 N/A physical interaction ComPPI
STAM TRIM54 25348397 N/A physical interaction ComPPI
STAM USP15 25348397 N/A physical interaction ComPPI
STAM USP28 25348397 N/A physical interaction ComPPI
STAM PRDX5 25348397 N/A physical interaction ComPPI
STAM AHCYL1 25348397 N/A physical interaction ComPPI
STAM USP34 25348397 N/A physical interaction ComPPI
STAM SULT1A1 25348397 N/A physical interaction ComPPI
STAM STUB1 25348397 N/A physical interaction ComPPI
STAM TBCK 25348397 N/A physical interaction ComPPI
STAM THADA 25348397 N/A physical interaction ComPPI
STAM ZPR1 25348397 N/A physical interaction ComPPI
STAM PPM1G 25348397 N/A physical interaction ComPPI
STAM UNK 25348397 N/A physical interaction ComPPI
STAM UBE4B 25348397 N/A physical interaction ComPPI
STAM DTX3L 25348397 N/A physical interaction ComPPI
STAM MAP3K1 25348397 N/A physical interaction ComPPI
STAM FBF1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STAM TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STAM TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STAM PMEPA1 25348397 N/A physical interaction ComPPI
STAM PTPRN2 25348397 N/A physical interaction ComPPI
STAM TPTE 25348397 N/A physical interaction ComPPI
STAM TRAF7 25348397 N/A physical interaction ComPPI
STAM NCEH1 25348397 N/A physical interaction ComPPI
STAM BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STAM TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PTPN23 STAM 25348397 N/A physical interaction ComPPI
ARRB1 STAM 20505072 27898060 N/A N/A OmniPath
JAK3 STAM 10899310 27898060 9133424 stimulant N/A OmniPath
CAMK2A STAM 10993906 11687594 27898060 N/A N/A OmniPath
JAK2 STAM 27898060 9133424 stimulant N/A OmniPath

Visualization










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