Gene Information gene info

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GENE：TOB2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TOB2
FullNmae transducer of ERBB2, 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11980
EnsembleID ENSG00000183864
Uniprot Q14106

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TOB2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TOB2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TOB2 GO:0003714,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0007292,GO:0008285,GO:0010468,GO:0030316,GO:0042809,GO:0045671,GO:0045778,GO:0045892

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TOB2 hsa:10766 path:hsa03018 RNA degradation - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 TOB2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
GATA2 TOB2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 TOB2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TOB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TOB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TOB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TOB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TOB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TOB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TOB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR TOB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TOB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070CD2 TOB2 22012620 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000451A1 TOB2 21242960 rna interference,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000451A1 TOB2 21242960 25416803 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000070CD2 TOB2 22012620 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00003380CC TOB2 17612493 20371350 23592263 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS0000070B1D TOB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE TOB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 TOB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD TOB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 TOB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001012BC TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017CCCB TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001A122A TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002578DA TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075A608 TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 TOB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001383CF TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002E728C TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001DABC0 TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005F9738 TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005485E8 TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A TOB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 TOB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 TOB2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 TOB2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 TOB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003ACE11 TOB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 TOB2 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TOB2 CNOT7 25361965 interaction type N/A PTMCode2
CNOT7 TOB2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BHLHE40 TOB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NANOS2 TOB2 25348397 N/A physical interaction ComPPI
CHAF1A TOB2 25348397 N/A physical interaction ComPPI
RPS6KA1 TOB2 11260258 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
UBR5 TOB2 25348397 N/A physical interaction ComPPI
PABPC1 TOB2 23340509 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPO1 TOB2 25348397 N/A physical interaction ComPPI
ELAVL1 TOB2 25348397 N/A physical interaction ComPPI
CNOT7 TOB2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CNOT8 TOB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TOB2 PAN2 25348397 N/A physical interaction ComPPI
TOB2 CEP76 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TOB2 CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOB2 RIBC1 25348397 N/A physical interaction ComPPI
TOB2 CPEB3 21336257 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
TOB2 TOB2 10602502 14525934 N/A experimental interaction detection,two hybrid HPRD

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