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GENE：UBE2H

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBE2H
FullNmae ubiquitin conjugating enzyme E2 H
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12484
EnsembleID ENSG00000186591
Uniprot P62256

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBE2H autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UBE2H GO:0000209,GO:0004842,GO:0005515,GO:0005524,GO:0005634,GO:0005829,GO:0006511,GO:0043161,GO:0061631,GO:0070936,GO:0070979

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UBE2H hsa:7328 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BYSL UBE2H 23180781 25416956 physical association two hybrid InnateDB
UBE2H ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR UBE2H 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 UBE2H 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 UBE2H 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 UBE2H 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 UBE2H 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 UBE2H 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 UBE2H 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TAL1 UBE2H 18971253 20028976 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C UBE2H 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 UBE2H 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 UBE2H 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 UBE2H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UBE2H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBE2H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UBE2H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UBE2H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UBE2H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 UBE2H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 UBE2H 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002E857A UBE2H 20218812 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 UBE2H 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000065D58 UBE2H 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000EEE35 UBE2H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 UBE2H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000027080C UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000610EFA UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 UBE2H 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF UBE2H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 UBE2H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A UBE2H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 UBE2H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D UBE2H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C UBE2H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 UBE2H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000059EB31 UBE2H 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 UBE2H 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 UBE2H 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 UBE2H 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA UBE2H 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 UBE2H 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 UBE2H 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 UBE2H 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B UBE2H 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 UBE2H 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 UBE2H 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 UBE2H 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 UBE2H 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 UBE2H 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 UBE2H 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BYSL UBE2H 25348397 N/A physical interaction ComPPI
GOLGA2 UBE2H 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
TRIM21 UBE2H 25348397 N/A physical interaction ComPPI
UBASH3B UBE2H 25348397 N/A physical interaction ComPPI
MAGEA2 UBE2H 20864041 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down ComPPI,IntAct
MKRN3 UBE2H 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TXNDC17 UBE2H 25348397 N/A physical interaction ComPPI
MAGEC2 UBE2H 20864041 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,ubiquitinase assay ComPPI,IntAct
CBLC UBE2H 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
COPS5 UBE2H 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
FHOD1 UBE2H 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
POLL UBE2H 25348397 N/A physical interaction ComPPI
POLM UBE2H 25348397 N/A physical interaction ComPPI
PRDX1 UBE2H 25348397 N/A physical interaction ComPPI
RMND5B UBE2H 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
STAM2 UBE2H 25348397 N/A physical interaction ComPPI
HNRNPL UBE2H 25348397 N/A physical interaction ComPPI
RELA UBE2H 25348397 N/A physical interaction ComPPI
UBR2 UBE2H 25348397 N/A physical interaction ComPPI
RAG1 UBE2H 25348397 N/A physical interaction ComPPI
H2AC18 UBE2H 14525934 25348397 27898060 8543049 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
EPS15 UBE2H 25348397 N/A physical interaction ComPPI
TRIM23 UBE2H 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CDK2 UBE2H 25348397 N/A physical interaction ComPPI
HDAC2 UBE2H 25348397 N/A physical interaction ComPPI
RNF2 UBE2H 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM28 UBE2H 25348397 N/A physical interaction ComPPI
HDAC6 UBE2H 25348397 N/A physical interaction ComPPI
ZBTB17 UBE2H 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TRAIP UBE2H 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DNM1L UBE2H 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
RNF139 UBE2H 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
JADE1 UBE2H 25348397 N/A physical interaction ComPPI
PRKN UBE2H 25348397 N/A physical interaction ComPPI
RNF128 UBE2H 25348397 N/A physical interaction ComPPI
RNF4 UBE2H 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBA1 UBE2H 25348397 N/A physical interaction ComPPI
DHPS UBE2H 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
PSME3 UBE2H 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
ELAVL1 UBE2H 25348397 N/A physical interaction ComPPI
RNF216 UBE2H 25348397 N/A physical interaction ComPPI
MARCHF8 UBE2H 25348397 N/A physical interaction ComPPI
UBAP2L UBE2H 25348397 N/A physical interaction ComPPI
UBE2H MARCHF2 14525934 14722266 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
UBE2H CD99 14525934 15388255 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
UBE2H RNF103 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H NEURL1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF186 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H TRIM56 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H UBOX5 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H DZIP3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF34 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H TRIM27 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H TRIM36 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H DTX3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF114 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H BRAP 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H LRSAM1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H DTX3L 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF10 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF113B 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF133 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF144A 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF146 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF166 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF185 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H MARCHF10 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF38 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H RNF6 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H TRIM17 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H TRIM2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H TRIM37 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H TRIM5 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2H SEC23IP 25348397 N/A physical interaction ComPPI
UBE2H TXNL1 25348397 N/A physical interaction ComPPI
UBE2H UBA3 25348397 N/A physical interaction ComPPI
UBE2H SSU72 25348397 N/A physical interaction ComPPI
UBE2H THOP1 25348397 N/A physical interaction ComPPI
UBE2H PRDX2 25348397 N/A physical interaction ComPPI
UBE2H USP5 25348397 N/A physical interaction ComPPI
UBE2H UFC1 25348397 N/A physical interaction ComPPI
UBE2H TRIM72 23965929 25348397 27898060 N/A physical interaction ComPPI,OmniPath
UBE2H ANXA6 25348397 N/A physical interaction ComPPI
UBE2H IDH1 25348397 N/A physical interaction ComPPI
UBE2H MTAP 25348397 N/A physical interaction ComPPI
UBE2H GOT1 25348397 N/A physical interaction ComPPI
UBE2H PTK2 25348397 N/A physical interaction ComPPI
UBE2H NHLRC1 15930137 24234451 25348397 physical association physical interaction,ubiquitinase assay ComPPI,IntAct
UBE2H UBR3 25348397 N/A physical interaction ComPPI
UBE2H TRIM69 25348397 N/A physical interaction ComPPI
UBE2H WDR26 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
UBE2H ARMC8 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2H MRPL38 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
LNX2 UBE2H 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LACTB2 UBE2H 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009B3D45 UBE2H 27087310 direct interaction,inhibition N/A NPInter

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