GENE：B3GAT3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | B3GAT3 |
| FullNmae | beta-1,3-glucuronyltransferase 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:923 |
| EnsembleID | ENSG00000149541 |
| Uniprot | O94766 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| B3GAT3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| B3GAT3 | GO:0000139,GO:0000139,GO:0005515,GO:0005794,GO:0005801,GO:0005975,GO:0006024,GO:0006024,GO:0006024,GO:0015012,GO:0015012,GO:0015018,GO:0015018,GO:0015020,GO:0015020,GO:0016020,GO:0016020,GO:0043085,GO:0046872,GO:0050650,GO:0050650,GO:0050650,GO:0050651,GO:0050651,GO:0070062,GO:0072542,GO:0090316 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| B3GAT3 | hsa:26229 | path:hsa00532 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate - Homo sapiens (human) |
| B3GAT3 | hsa:26229 | path:hsa00534 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin - Homo sapiens (human) |
| B3GAT3 | hsa:26229 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR2 | B3GAT3 | 20034404 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | B3GAT3 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | B3GAT3 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | B3GAT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | B3GAT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | B3GAT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | B3GAT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | B3GAT3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CREB1 | B3GAT3 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| STAT1 | B3GAT3 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| STAT3 | B3GAT3 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PTPRO | B3GAT3 | 25348397 | N/A | physical interaction | ComPPI |
| LEMD3 | B3GAT3 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPD | B3GAT3 | 25348397 | N/A | physical interaction | ComPPI |
| SEC62 | B3GAT3 | 25348397 | N/A | physical interaction | ComPPI |
| STX6 | B3GAT3 | 25348397 | N/A | physical interaction | ComPPI |
| NLGN1 | B3GAT3 | 25348397 | N/A | physical interaction | ComPPI |
| NLGN2 | B3GAT3 | 25348397 | N/A | physical interaction | ComPPI |
| SEC22B | B3GAT3 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| B3GAT3 | HMGCR | 25348397 | N/A | physical interaction | ComPPI |
| B3GAT3 | KCNC4 | 25348397 | N/A | physical interaction | ComPPI |
| CCR2 | B3GAT3 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
| CCR4 | B3GAT3 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |