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GENE：ADAMTS3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ADAMTS3
FullNmae ADAM metallopeptidase with thrombospondin type 1 motif 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:219
EnsembleID ENSG00000156140
Uniprot O15072

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ADAMTS3 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ADAMTS3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ADAMTS3 GO:0001701,GO:0004175,GO:0004222,GO:0004222,GO:0004222,GO:0005515,GO:0005576,GO:0005615,GO:0006508,GO:0008201,GO:0008270,GO:0010573,GO:0016485,GO:0030198,GO:0030199,GO:0030199,GO:0030199,GO:0030574,GO:0031012,GO:0031012,GO:0032964,GO:0062023,GO:0070062,GO:0097435,GO:1900748

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 ADAMTS3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ADAMTS3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 ADAMTS3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 ADAMTS3 21245298 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 ADAMTS3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ADAMTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ADAMTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ADAMTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ADAMTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ADAMTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ADAMTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ADAMTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ADAMTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ADAMTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ADAMTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AR ADAMTS3 N/A trascriptional regulation,stimulation inferred by curator TFlink
PPARG ADAMTS3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
UBQLN2 ADAMTS3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSP90B1 ADAMTS3 24234451 30021884 physical association cross-linking study IntAct

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