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GENE：UGDH

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UGDH
FullNmae UDP-glucose 6-dehydrogenase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12525
EnsembleID ENSG00000109814
Uniprot O60701

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UGDH autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UGDH GO:0001702,GO:0003979,GO:0005634,GO:0005654,GO:0005829,GO:0005975,GO:0006024,GO:0006065,GO:0006065,GO:0015012,GO:0030206,GO:0034214,GO:0042802,GO:0048666,GO:0051287,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UGDH hsa:7358 path:hsa00040 Pentose and glucuronate interconversions - Homo sapiens (human)
UGDH hsa:7358 path:hsa00053 Ascorbate and aldarate metabolism - Homo sapiens (human)
UGDH hsa:7358 path:hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human)
UGDH hsa:7358 path:hsa01100 Metabolic pathways - Homo sapiens (human)
UGDH hsa:7358 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)
UGDH hsa:7358 path:hsa01250 Biosynthesis of nucleotide sugars - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR UGDH 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 UGDH 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 UGDH 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SP1 UGDH 12682078 16002992 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 UGDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UGDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UGDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UGDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UGDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UGDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UGDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 UGDH 12682078 16002992 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171CD1 UGDH 18362358 rna interference,inhibition array technology miRSponge
URS0000171CD1 UGDH 18362358 25416803 mrna cleavage,inhibition array technology TarBase
URS0000237AF9 UGDH 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 UGDH 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000065D58 UGDH 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003ABC4 UGDH 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000075A608 UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075D814 UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075CC78 UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000209F04 UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000136174 UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005CCD18 UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000486E0B UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001012BC UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003AD2AA UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000023133F UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000043C1C3 UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000021202F UGDH 21572407 23446348 23706177 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001FC26E UGDH 22012620 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 UGDH 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D UGDH 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0920 UGDH 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 UGDH 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000003FD55 UGDH 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 UGDH 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 UGDH 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A UGDH 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 UGDH 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 UGDH 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 UGDH 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 UGDH 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000B989F UGDH 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039A052 UGDH 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000045147B UGDH 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001A7F58 UGDH 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 UGDH 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
CIAO1 UGDH 25348397 N/A physical interaction ComPPI
BAG3 UGDH 25348397 N/A physical interaction ComPPI
GTF2A1 UGDH 25348397 N/A physical interaction ComPPI
GRB2 UGDH 12577067 24234451 25348397 association pull down ComPPI,IntAct
PRKACA UGDH 25348397 N/A physical interaction ComPPI
PDIA6 UGDH 25348397 N/A physical interaction ComPPI
NTRK1 UGDH 25348397 N/A physical interaction ComPPI
SNX1 UGDH 25348397 N/A physical interaction ComPPI
XPO5 UGDH 25348397 N/A physical interaction ComPPI
GORASP2 UGDH 25348397 N/A physical interaction ComPPI
CFTR UGDH 25348397 N/A physical interaction ComPPI
RAD51 UGDH 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CTTN UGDH 25348397 N/A physical interaction ComPPI
HSPB1 UGDH 25348397 N/A physical interaction ComPPI
SIRT1 UGDH 25348397 N/A physical interaction ComPPI
GARS1 UGDH 25348397 N/A physical interaction ComPPI
TRIM25 UGDH 25348397 N/A physical interaction ComPPI
ELAVL1 UGDH 25348397 N/A physical interaction ComPPI
MAT2B UGDH 25348397 N/A physical interaction ComPPI
MAT2A UGDH 25348397 N/A physical interaction ComPPI
IMPA1 UGDH 25348397 N/A physical interaction ComPPI
TERF2 UGDH 25348397 N/A physical interaction ComPPI
TGOLN2 UGDH 25348397 N/A physical interaction ComPPI
UBE2V1 UGDH 25348397 N/A physical interaction ComPPI
FAS UGDH 25348397 N/A physical interaction ComPPI
ATG7 UGDH 25348397 N/A physical interaction ComPPI
BOP1 UGDH 25348397 N/A physical interaction ComPPI
SIRT3 UGDH 19343720 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
ITGB1BP2 UGDH 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
TKT UGDH 25348397 N/A physical interaction ComPPI
UGDH AK5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UGDH UGT1A1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UGDH ME1 25348397 N/A physical interaction ComPPI
UGDH RNASEH2A 25348397 N/A physical interaction ComPPI
UGDH RPUSD2 25348397 N/A physical interaction ComPPI
UGDH NAAA 25348397 N/A physical interaction ComPPI
UGDH TRAPPC4 25348397 N/A physical interaction ComPPI
UGDH LAMP3 25348397 N/A physical interaction ComPPI
UGDH FAM174A 25348397 N/A physical interaction ComPPI
UGDH DKKL1 25348397 N/A physical interaction ComPPI
GGH UGDH 25348397 N/A physical interaction ComPPI
UGDH UGDH 24234451 25416956 physical association two hybrid array IntAct

Visualization










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