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GENE：SETMAR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SETMAR
FullNmae SET domain and mariner transposase fusion gene
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10762
EnsembleID ENSG00000170364
Uniprot Q53H47

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SETMAR parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SETMAR mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SETMAR autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SETMAR GO:0000014,GO:0000014,GO:0000729,GO:0000729,GO:0000793,GO:0000793,GO:0003677,GO:0003677,GO:0003690,GO:0003690,GO:0003697,GO:0003697,GO:0004519,GO:0004519,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005730,GO:0006303,GO:0006303,GO:0006303,GO:0006308,GO:0006308,GO:0006338,GO:0008270,GO:0008283,GO:0015074,GO:0015074,GO:0031297,GO:0031297,GO:0032259,GO:0035861,GO:0035861,GO:0035861,GO:0042800,GO:0042800,GO:0042803,GO:0044547,GO:0044547,GO:0044774,GO:0044774,GO:0046975,GO:0046975,GO:0046975,GO:0090305,GO:0140954,GO:2000373,GO:2000373,GO:2001034,GO:2001251

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SETMAR hsa:6419 path:hsa00310 Lysine degradation - Homo sapiens (human)
SETMAR hsa:6419 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SOX11 SETMAR 23180781 24681958 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 SETMAR 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SETMAR 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SETMAR 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 SETMAR 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SETMAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SETMAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SETMAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CHEK1 SETMAR 22135298 phosphorylation N/A PhosphoSite
SETMAR TOP2A 25361965 interaction type N/A PTMCode2
TOP2A SETMAR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
YJU2 SETMAR 25348397 N/A physical interaction ComPPI
HSPA8 SETMAR 25348397 N/A physical interaction ComPPI
PCBP1 SETMAR 25348397 N/A physical interaction ComPPI
PCNA SETMAR 25348397 N/A physical interaction ComPPI
RAD9A SETMAR 25348397 N/A physical interaction ComPPI
CHEK1 SETMAR 25348397 N/A physical interaction ComPPI
IKZF3 SETMAR 25348397 N/A physical interaction ComPPI
DOC2A SETMAR 25348397 N/A physical interaction ComPPI
TOP2A SETMAR 18790802 19458360 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PRPF19 SETMAR 25348397 N/A physical interaction ComPPI
LEO1 SETMAR 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SETMAR XRCC4 25348397 N/A physical interaction ComPPI
SETMAR SETX 25348397 N/A physical interaction ComPPI
H3-5 SETMAR 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SETMAR SETMAR 14525934 16169070 24234451 physical association two hybrid pooling approach,two hybrid HPRD,IntAct
CHEK1 SETMAR 22231448 25024738 27898060 N/A N/A OmniPath

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