GENE：PLPP1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PLPP1 |
| FullNmae | phospholipid phosphatase 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9228 |
| EnsembleID | ENSG00000067113 |
| Uniprot | O14494 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PLPP1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PLPP1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PLPP1 | GO:0000810,GO:0005515,GO:0005886,GO:0005886,GO:0005901,GO:0006644,GO:0006644,GO:0006644,GO:0006670,GO:0006672,GO:0007165,GO:0007165,GO:0007205,GO:0008195,GO:0008195,GO:0008195,GO:0008285,GO:0016020,GO:0016324,GO:0019216,GO:0030148,GO:0030518,GO:0030521,GO:0042392,GO:0042392,GO:0042577,GO:0045121,GO:0046839,GO:0046839,GO:0046839,GO:0070062,GO:0106235 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PLPP1 | hsa:8611 | path:hsa00561 | Glycerolipid metabolism - Homo sapiens (human) |
| PLPP1 | hsa:8611 | path:hsa00564 | Glycerophospholipid metabolism - Homo sapiens (human) |
| PLPP1 | hsa:8611 | path:hsa00565 | Ether lipid metabolism - Homo sapiens (human) |
| PLPP1 | hsa:8611 | path:hsa00600 | Sphingolipid metabolism - Homo sapiens (human) |
| PLPP1 | hsa:8611 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| PLPP1 | hsa:8611 | path:hsa04072 | Phospholipase D signaling pathway - Homo sapiens (human) |
| PLPP1 | hsa:8611 | path:hsa04666 | Fc gamma R-mediated phagocytosis - Homo sapiens (human) |
| PLPP1 | hsa:8611 | path:hsa04975 | Fat digestion and absorption - Homo sapiens (human) |
| PLPP1 | hsa:8611 | path:hsa05231 | Choline metabolism in cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PLPP1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA3 | PLPP1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | PLPP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PLPP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PLPP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PLPP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PLPP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | PLPP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | PLPP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HNRNPL | PLPP1 | 25348397 | N/A | physical interaction | ComPPI |
| FXYD1 | PLPP1 | 10087003 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| CREB3 | PLPP1 | 21516116 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PLPP1 | ILF3 | 25348397 | N/A | physical interaction | ComPPI |
| PLPP1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |