Gene Information gene info

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GENE：DHX8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DHX8
FullNmae DEAH-box helicase 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2749
EnsembleID ENSG00000067596
Uniprot Q14562

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DHX8 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DHX8 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DHX8 GO:0000390,GO:0000398,GO:0000398,GO:0000398,GO:0003723,GO:0003723,GO:0003724,GO:0005515,GO:0005524,GO:0005622,GO:0005634,GO:0005654,GO:0005654,GO:0005681,GO:0005829,GO:0006396,GO:0008186,GO:0008380,GO:0016604,GO:0016887,GO:0042802,GO:0071007,GO:0071013,GO:0071013

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DHX8 hsa:1659 path:hsa03040 Spliceosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMAD2 DHX8 18729074 23180781 physical association tandem affinity purification InnateDB
SMAD3 DHX8 18729074 23180781 physical association tandem affinity purification InnateDB
TLR2 DHX8 21827211 23180781 physical association anti tag coimmunoprecipitation InnateDB
SRPK1 DHX8 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB
SRPK2 DHX8 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 DHX8 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 DHX8 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DHX8 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 DHX8 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DHX8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DHX8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DHX8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DHX8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 DHX8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DHX8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DHX8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN DHX8 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A DHX8 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 DHX8 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000079D48 DHX8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000033EBB8 DHX8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC DHX8 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
DHX8 CDC40 25361965 interaction type N/A PTMCode2
CDC40 DHX8 25361965 interaction type N/A PTMCode2
DHX8 CRNKL1 25361965 interaction type N/A PTMCode2
CRNKL1 DHX8 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MFAP1 DHX8 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KANSL1 DHX8 25348397 N/A physical interaction ComPPI
SNW1 DHX8 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L DHX8 25348397 N/A physical interaction ComPPI
SAP30BP DHX8 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CD2BP2 DHX8 25348397 N/A physical interaction ComPPI
BAG3 DHX8 25348397 N/A physical interaction ComPPI
TAF9 DHX8 25348397 N/A physical interaction ComPPI
RPL36AL DHX8 25348397 N/A physical interaction ComPPI
SNIP1 DHX8 25348397 N/A physical interaction ComPPI
RPL10A DHX8 25348397 N/A physical interaction ComPPI
NOTCH1 DHX8 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
JUN DHX8 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
SMAD2 DHX8 18729074 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
SMAD3 DHX8 18729074 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
RPL18A DHX8 25348397 N/A physical interaction ComPPI
CUL3 DHX8 25348397 N/A physical interaction ComPPI
NTRK1 DHX8 25348397 N/A physical interaction ComPPI
ENO1 DHX8 25348397 N/A physical interaction ComPPI
PRPF40A DHX8 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
XRN2 DHX8 25348397 N/A physical interaction ComPPI
XAB2 DHX8 25348397 N/A physical interaction ComPPI
THOC1 DHX8 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SRPK1 DHX8 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
MYPN DHX8 25348397 N/A physical interaction ComPPI
MAP1LC3A DHX8 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CAND1 DHX8 25348397 N/A physical interaction ComPPI
RPL5 DHX8 25348397 N/A physical interaction ComPPI
TRIM25 DHX8 25348397 N/A physical interaction ComPPI
SRPK2 DHX8 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
MAGOH DHX8 23084401 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PNN DHX8 25348397 N/A physical interaction ComPPI
RBM7 DHX8 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
IFI16 DHX8 25348397 N/A physical interaction ComPPI
CDC40 DHX8 25348397 N/A physical interaction ComPPI
SHMT2 DHX8 25348397 N/A physical interaction ComPPI
POLR1B DHX8 25348397 N/A physical interaction ComPPI
PRPF19 DHX8 25348397 N/A physical interaction ComPPI
DLST DHX8 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CDX1 DHX8 25348397 N/A physical interaction ComPPI
FTSJ3 DHX8 25348397 N/A physical interaction ComPPI
PPIE DHX8 25348397 N/A physical interaction ComPPI
ZCCHC10 DHX8 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NKAP DHX8 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
EAPP DHX8 25348397 N/A physical interaction ComPPI
TSSC4 DHX8 25348397 N/A physical interaction ComPPI
SIRT7 DHX8 25348397 N/A physical interaction ComPPI
RPL26 DHX8 25348397 N/A physical interaction ComPPI
PRPF38A DHX8 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RPL15 DHX8 25348397 N/A physical interaction ComPPI
CRNKL1 DHX8 25348397 N/A physical interaction ComPPI
AHCYL1 DHX8 25348397 N/A physical interaction ComPPI
NOP2 DHX8 25348397 N/A physical interaction ComPPI
CACTIN DHX8 25348397 N/A physical interaction ComPPI
AK6 DHX8 25348397 N/A physical interaction ComPPI
NXF1 DHX8 25348397 N/A physical interaction ComPPI
RPL32 DHX8 25348397 N/A physical interaction ComPPI
MOV10 DHX8 25348397 N/A physical interaction ComPPI
DDX41 DHX8 24234451 25348397 25920683 association anti tag coimmunoprecipitation ComPPI,IntAct
RSL1D1 DHX8 25348397 N/A physical interaction ComPPI
PHF5A DHX8 25348397 N/A physical interaction ComPPI
CHERP DHX8 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
USP12 DHX8 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX8 ISY1 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
DHX8 RBMX2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DHX8 LIN28A 25348397 N/A physical interaction ComPPI
DHX8 NUDCD1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX8 OBSL1 25348397 N/A physical interaction ComPPI
DHX8 RPL26L1 25348397 N/A physical interaction ComPPI
DHX8 RBM28 25348397 N/A physical interaction ComPPI
DHX8 NKAPD1 25348397 N/A physical interaction ComPPI
DHX8 AQR 25348397 N/A physical interaction ComPPI
DHX8 MORC2 25348397 N/A physical interaction ComPPI
DHX8 AHCYL2 25348397 N/A physical interaction ComPPI
DHX8 CCDC12 25348397 N/A physical interaction ComPPI
DHX8 JMJD6 25348397 N/A physical interaction ComPPI
DHX8 CHCHD10 25348397 N/A physical interaction ComPPI
DHX8 H1-6 25348397 N/A physical interaction ComPPI
DHX8 SYF2 25348397 N/A physical interaction ComPPI
DHX8 DHX8 22365833 24234451 physical association anti tag coimmunoprecipitation,two hybrid IntAct
FLNA DHX8 24234451 30021884 physical association cross-linking study IntAct

Visualization










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