GENE：COA1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | COA1 |
| FullNmae | cytochrome c oxidase assembly factor 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:21868 |
| EnsembleID | ENSG00000106603 |
| Uniprot | Q9GZY4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| COA1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| COA1 | GO:0005515,GO:0005739,GO:0005743,GO:0005743,GO:0005743,GO:0005829,GO:0032981,GO:0032981,GO:0032981,GO:0033617,GO:0033617 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| COA1 | hsa:55744 | path:hsa04714 | Thermogenesis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | COA1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | COA1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | COA1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | COA1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | COA1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | COA1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000122ED0 | COA1 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002075FA | COA1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000192A75 | COA1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001310DE | COA1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000081D1E | COA1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000049FAE8 | COA1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| COX17 | COA1 | 25348397 | N/A | physical interaction | ComPPI |
| STK4 | COA1 | 23386615 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
| COPS6 | COA1 | 25348397 | N/A | physical interaction | ComPPI |
| MT-CO1 | COA1 | 23260140 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| ECSIT | COA1 | 25348397 | N/A | physical interaction | ComPPI |
| NCDN | COA1 | 25348397 | N/A | physical interaction | ComPPI |
| NDUFB8 | COA1 | 23260140 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| PHLPP1 | COA1 | 25348397 | N/A | physical interaction | ComPPI |
| ACAD9 | COA1 | 25348397 | N/A | physical interaction | ComPPI |
| RFWD3 | COA1 | 25348397 | N/A | physical interaction | ComPPI |
| COA1 | SURF1 | 23260140 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |