GENE：FAM102A
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | FAM102A |
| FullNmae | estrogen-induced osteoclastogenesis regulator 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:31419 |
| EnsembleID | ENSG00000167106 |
| Uniprot | Q5T9C2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| FAM102A | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | FAM102A | 18414489 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,chromatin immunoprecipitation assay | TFlink |
| ETS1 | FAM102A | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | FAM102A | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | FAM102A | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | FAM102A | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | FAM102A | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | FAM102A | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | FAM102A | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | FAM102A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | FAM102A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | FAM102A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | FAM102A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | FAM102A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | FAM102A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | FAM102A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | FAM102A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | FAM102A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | FAM102A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | FAM102A | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00003380CC | FAM102A | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001C3AC1 | FAM102A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003CF1AD | FAM102A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000042E1F | FAM102A | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | FAM102A | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | FAM102A | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | FAM102A | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | FAM102A | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | FAM102A | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | FAM102A | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CC709 | FAM102A | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000008A99 | FAM102A | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C4DB5 | FAM102A | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000122F23 | FAM102A | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001496AE | FAM102A | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000020CEC2 | FAM102A | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SKAP1 | FAM102A | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| SERPINB8 | FAM102A | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | FAM102A | 25348397 | N/A | physical interaction | ComPPI |
| SH3GL1 | FAM102A | 25348397 | N/A | physical interaction | ComPPI |
| NUP160 | FAM102A | 25348397 | N/A | physical interaction | ComPPI |
| ESR1 | FAM102A | 14605097 27898060 | stimulant | N/A | OmniPath |