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GENE：ZFP36L1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ZFP36L1
FullNmae ZFP36 ring finger protein like 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1107
EnsembleID ENSG00000185650
Uniprot Q07352

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ZFP36L1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ZFP36L1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ZFP36L1 GO:0000165,GO:0000288,GO:0000932,GO:0001570,GO:0003342,GO:0003677,GO:0003723,GO:0003729,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0006397,GO:0006915,GO:0007507,GO:0008283,GO:0009611,GO:0010468,GO:0010837,GO:0021915,GO:0031086,GO:0031440,GO:0032869,GO:0033077,GO:0035264,GO:0035925,GO:0038066,GO:0043488,GO:0043488,GO:0043491,GO:0043491,GO:0044344,GO:0045577,GO:0045600,GO:0045616,GO:0045647,GO:0045657,GO:0045661,GO:0046872,GO:0048382,GO:0051028,GO:0060710,GO:0061158,GO:0061158,GO:0070371,GO:0071320,GO:0071356,GO:0071364,GO:0071375,GO:0071385,GO:0071456,GO:0071472,GO:0071560,GO:0071889,GO:0072091,GO:0097403,GO:1900153,GO:1901991,GO:1902172,GO:1904582,GO:1990904

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ZFP36L1 hsa:677 path:hsa04218 Cellular senescence - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ZFP36L1 AKT2 15538381 17030608 23180781 phosphorylation reaction in-gel kinase assay,protein kinase assay InnateDB
ZFP36L1 MAPK3 17030608 23180781 phosphorylation reaction in-gel kinase assay InnateDB
ZFP36L1 MAPK14 16189514 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR ZFP36L1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 ZFP36L1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 ZFP36L1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ZFP36L1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ZFP36L1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A ZFP36L1 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
MYC ZFP36L1 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 ZFP36L1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ZFP36L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ZFP36L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ZFP36L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ZFP36L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ZFP36L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ZFP36L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ZFP36L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ZFP36L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ZFP36L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ZFP36L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ZFP36L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 ZFP36L1 17942906 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS00000BE495 ZFP36L1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000202460 ZFP36L1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 ZFP36L1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 ZFP36L1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE ZFP36L1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 ZFP36L1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 ZFP36L1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 ZFP36L1 19536157 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000005CF5F ZFP36L1 19536157 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001DE669 ZFP36L1 19536157 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000031BC7D ZFP36L1 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F ZFP36L1 21572407 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 ZFP36L1 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F ZFP36L1 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 ZFP36L1 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 ZFP36L1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 ZFP36L1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D ZFP36L1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002578DA ZFP36L1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C ZFP36L1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 ZFP36L1 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075C4B1 ZFP36L1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000034979B ZFP36L1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001A405B ZFP36L1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000302909 ZFP36L1 20371350 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000013E79D ZFP36L1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED ZFP36L1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D ZFP36L1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075D50C ZFP36L1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 ZFP36L1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 ZFP36L1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC ZFP36L1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 ZFP36L1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 ZFP36L1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001D4A78 ZFP36L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001CC379 ZFP36L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000345DEB ZFP36L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002152A8 ZFP36L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006B702 ZFP36L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002FAA8C ZFP36L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AA845 ZFP36L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 ZFP36L1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000016FF9C ZFP36L1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPKAPK2 ZFP36L1 22135298 phosphorylation N/A PhosphoSite
PRKACA ZFP36L1 22135298 phosphorylation N/A PhosphoSite
AKT1 ZFP36L1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
RBM8A ZFP36L1 25348397 N/A physical interaction ComPPI
MAPK14 ZFP36L1 14525934 16189514 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct
YWHAB ZFP36L1 25348397 N/A physical interaction ComPPI
YWHAZ ZFP36L1 15538381 24234451 25348397 association coimmunoprecipitation ComPPI,IntAct
XPO1 ZFP36L1 25348397 N/A physical interaction ComPPI
MAPKAPK2 ZFP36L1 25348397 N/A physical interaction ComPPI
SF1 ZFP36L1 24234451 25348397 26420826 physical association two hybrid fragment pooling approach ComPPI,IntAct
TFAP2C ZFP36L1 24234451 24835590 25348397 physical association two hybrid ComPPI,IntAct
ELAVL1 ZFP36L1 25348397 N/A physical interaction ComPPI
TERF1 ZFP36L1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
POT1 ZFP36L1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TINF2 ZFP36L1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
AKT1 ZFP36L1 25348397 N/A physical interaction ComPPI
PAFAH1B2 ZFP36L1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
DCP2 ZFP36L1 25348397 N/A physical interaction ComPPI
EXOSC2 ZFP36L1 25348397 N/A physical interaction ComPPI
CNOT6 ZFP36L1 25348397 N/A physical interaction ComPPI
ACD ZFP36L1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
MAPKAPK2 ZFP36L1 18326031 26280535 27898060 inhibition N/A OmniPath
AKT1 ZFP36L1 15538381 17030608 27898060 inhibition N/A OmniPath
MAPK3 ZFP36L1 17030608 27898060 N/A N/A OmniPath
ZFP36L1 MAPK14 16189514 17030608 27898060 N/A N/A OmniPath
MAPK14 ZFP36L1 15538381 16189514 17030608 27898060 N/A N/A OmniPath
AKT2 ZFP36L1 15538381 17030608 27898060 N/A N/A OmniPath

Visualization










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