Gene Information gene info

GENE:KLF3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KLF3
FullNmae KLF transcription factor 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16516
EnsembleID ENSG00000109787
Uniprot P57682

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KLF3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KLF3 GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0003700,GO:0005515,GO:0005654,GO:0006357,GO:0030097,GO:0046872,GO:1901653,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KLF3 hsa:51274 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR KLF3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 KLF3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 KLF3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 KLF3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 KLF3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 KLF3 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C KLF3 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 KLF3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 KLF3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 KLF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KLF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KLF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 KLF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KLF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS KLF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KLF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF KLF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 KLF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 KLF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 KLF3 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 KLF3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00001CC864 KLF3 23918807 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS00002075FA KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C KLF3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001F9A0F KLF3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000024B619 KLF3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 KLF3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 KLF3 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HIPK2 KLF3 22135298 phosphorylation N/A PhosphoSite
KLF3 CTBP2 25361965 interaction type N/A PTMCode2
CTBP2 KLF3 25361965 interaction type N/A PTMCode2
KLF3 FHL3 25361965 interaction type N/A PTMCode2
FHL3 KLF3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FHL3 KLF3 24234451 25348397 25416956 27107012 physical association physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid prey pooling approach,validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
EHMT2 KLF3 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CTBP1 KLF3 25348397 N/A physical interaction ComPPI
CTBP2 KLF3 14525934 25348397 9724649 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TRAF2 KLF3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRIM25 KLF3 25348397 N/A physical interaction ComPPI
DVL3 KLF3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KDM1A KLF3 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KLF3 SUV39H2 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KLF3 LHX8 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KLF3 LHX6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HIPK2 KLF3 25659434 27898060 N/A N/A OmniPath

Visualization