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GENE：PTBP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTBP2
FullNmae polypyrimidine tract binding protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17662
EnsembleID ENSG00000117569
Uniprot Q9UKA9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTBP2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTBP2 GO:0003723,GO:0003729,GO:0005634,GO:0005681,GO:0006376,GO:0033119,GO:0043484,GO:2000177

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PTBP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PTBP2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PTBP2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PTBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PTBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PTBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000032BD73 PTBP2 17210790 rna interference,inhibition experimental interaction detection,western blot miRSponge
URS000032BD73 PTBP2 17210790 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000F31F4 PTBP2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 PTBP2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B7E30 PTBP2 23174904 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000272039 PTBP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 PTBP2 23313552 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000258D51 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000020CEC2 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000195F5B PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004DA9DB PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000006FDD4 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000043D2C1 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004BC299 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000080D0A PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000008AA34 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002C02E4 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039A25B PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075B13F PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AEA5 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004283FE PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000118224 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000037B2E0 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000319E1 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000496C56 PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD02D PTBP2 20371350 21572407 23446348 23706177 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 PTBP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 PTBP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 PTBP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000015F70F PTBP2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0B46 PTBP2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 PTBP2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C PTBP2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 PTBP2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075E538 PTBP2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 PTBP2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C PTBP2 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GOLGA2 PTBP2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDC5L PTBP2 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SNRPA PTBP2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HNRNPC PTBP2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
STAT1 PTBP2 24234451 25348397 26966684 association pull down ComPPI,IntAct
UBE2E2 PTBP2 25348397 N/A physical interaction ComPPI
KHDRBS1 PTBP2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
JUN PTBP2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RBM4 PTBP2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HNRNPL PTBP2 25348397 N/A physical interaction ComPPI
RBM10 PTBP2 14525934 16189514 22365833 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
QKI PTBP2 14525934 16713569 22365833 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
KHDRBS3 PTBP2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ELAVL1 PTBP2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HNRNPD PTBP2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PUF60 PTBP2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KHSRP PTBP2 25348397 N/A physical interaction ComPPI
HNRNPAB PTBP2 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CALCOCO2 PTBP2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RRP1B PTBP2 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PTBP2 FUS 25348397 N/A physical interaction ComPPI
PTBP2 MATR3 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PTBP2 TOM1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTBP2 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PTBP2 IGF2BP1 19029303 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF5A2 PTBP2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRAF2 PTBP2 24234451 30561431 association virotrap IntAct
TNIP2 PTBP2 24234451 30561431 association virotrap IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B5F2A PTBP2 27087310 direct interaction,inhibition N/A NPInter

Visualization










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