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GENE：SEPHS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SEPHS1
FullNmae selenophosphate synthetase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19685
EnsembleID ENSG00000086475
Uniprot P49903

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SEPHS1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SEPHS1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SEPHS1 GO:0004756,GO:0005515,GO:0005524,GO:0005525,GO:0005737,GO:0005886,GO:0016260,GO:0016310,GO:0031965,GO:0036211,GO:0042802,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SEPHS1 hsa:22929 path:hsa00450 Selenocompound metabolism - Homo sapiens (human)
SEPHS1 hsa:22929 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 SEPHS1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 SEPHS1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 SEPHS1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SEPHS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SEPHS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SEPHS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SEPHS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SEPHS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 SEPHS1 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 SEPHS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE SEPHS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 SEPHS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002A8BC6 SEPHS1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B SEPHS1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F SEPHS1 22100165 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 SEPHS1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000553F51 SEPHS1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 SEPHS1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 SEPHS1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 SEPHS1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC SEPHS1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E SEPHS1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 SEPHS1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 SEPHS1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 SEPHS1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 SEPHS1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B SEPHS1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 SEPHS1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001FA076 SEPHS1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C36BD SEPHS1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 SEPHS1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC0F4 SEPHS1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A SEPHS1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 SEPHS1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 SEPHS1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D SEPHS1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F SEPHS1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075CC78 SEPHS1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075D814 SEPHS1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001012BC SEPHS1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000038446A SEPHS1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EIF1B SEPHS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
QRICH1 SEPHS1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCDC130 SEPHS1 25348397 N/A physical interaction ComPPI
SAT1 SEPHS1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ZBTB25 SEPHS1 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TUFM SEPHS1 25348397 N/A physical interaction ComPPI
CRKL SEPHS1 25348397 N/A physical interaction ComPPI
UNC119 SEPHS1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CUL3 SEPHS1 25348397 N/A physical interaction ComPPI
PTPRF SEPHS1 25348397 N/A physical interaction ComPPI
XPO1 SEPHS1 25348397 N/A physical interaction ComPPI
COPS2 SEPHS1 25348397 N/A physical interaction ComPPI
SOX2 SEPHS1 25348397 N/A physical interaction ComPPI
HSPB1 SEPHS1 25348397 N/A physical interaction ComPPI
WDR12 SEPHS1 25348397 N/A physical interaction ComPPI
CRMP1 SEPHS1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FDPS SEPHS1 25348397 N/A physical interaction ComPPI
XAF1 SEPHS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CLIC1 SEPHS1 25348397 N/A physical interaction ComPPI
PDCD6 SEPHS1 25348397 N/A physical interaction ComPPI
SEC13 SEPHS1 25348397 N/A physical interaction ComPPI
ELAVL1 SEPHS1 25348397 N/A physical interaction ComPPI
CLIC4 SEPHS1 25348397 N/A physical interaction ComPPI
XPO7 SEPHS1 25348397 N/A physical interaction ComPPI
TNFRSF10D SEPHS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DDX19B SEPHS1 25348397 N/A physical interaction ComPPI
SUGT1 SEPHS1 25348397 N/A physical interaction ComPPI
ERG28 SEPHS1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ECH1 SEPHS1 25348397 N/A physical interaction ComPPI
SEPHS1 GBP2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SEPHS1 AHCYL1 25348397 N/A physical interaction ComPPI
SEPHS1 DDX19A 25348397 N/A physical interaction ComPPI
SEPHS1 RTCB 25348397 N/A physical interaction ComPPI
SEPHS1 HLX 25348397 N/A physical interaction ComPPI
SEPHS1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
G6PD SEPHS1 25348397 N/A physical interaction ComPPI

Visualization










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