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GENE：NME3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NME3
FullNmae NME/NM23 nucleoside diphosphate kinase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7851
EnsembleID ENSG00000103024
Uniprot Q13232

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NME3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NME3 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NME3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NME3 GO:0004550,GO:0005515,GO:0005524,GO:0005829,GO:0006183,GO:0006228,GO:0006241,GO:0006915,GO:0016310,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NME3 hsa:4832 path:hsa00230 Purine metabolism - Homo sapiens (human)
NME3 hsa:4832 path:hsa00240 Pyrimidine metabolism - Homo sapiens (human)
NME3 hsa:4832 path:hsa00983 Drug metabolism - other enzymes - Homo sapiens (human)
NME3 hsa:4832 path:hsa01100 Metabolic pathways - Homo sapiens (human)
NME3 hsa:4832 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)
NME3 hsa:4832 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 NME3 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
APP NME3 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
TFAP2A NME3 9067290 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
EGR1 NME3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000005481D NME3 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
NME3 POLR1B 25361965 interaction type N/A PTMCode2
POLR1B NME3 25361965 interaction type N/A PTMCode2
NME3 NME1 25361965 interaction type N/A PTMCode2
NME1 NME3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SGTA NME3 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
NME3 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
NME3 HTR2A 14525934 16537434 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
NME3 NME1 11042679 14525934 16189514 24234451 25348397 25416956 physical association experimental interaction detection,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
NME3 NME2 11042679 14525934 16169070 24234451 25348397 physical association experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vivo ComPPI,HPRD,IntAct
NME3 APP 25348397 N/A physical interaction ComPPI
NME3 JAM2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NME3 UBQLN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NME3 RNF2 25348397 N/A physical interaction ComPPI
NME3 RPS6KB2 25348397 N/A physical interaction ComPPI
NME3 NMES1 25348397 N/A physical interaction ComPPI
NME3 NME4 25348397 N/A physical interaction ComPPI
NME3 DUSP22 25348397 N/A physical interaction ComPPI
NME3 DUSP23 25348397 N/A physical interaction ComPPI
NME3 DUSP6 25348397 N/A physical interaction ComPPI
NME3 DUSP9 25348397 N/A physical interaction ComPPI
NME3 BBS5 25348397 N/A physical interaction ComPPI
NME3 BBS9 25348397 N/A physical interaction ComPPI
NME3 BBS4 25348397 N/A physical interaction ComPPI
NME3 TTC8 25348397 N/A physical interaction ComPPI
NME3 EXD2 25348397 N/A physical interaction ComPPI
NME3 BBS7 25348397 N/A physical interaction ComPPI
NME3 BBS2 25348397 N/A physical interaction ComPPI
NME3 PEX14 25348397 N/A physical interaction ComPPI
NME3 AAR2 25348397 N/A physical interaction ComPPI
NME3 PHLDA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NME3 IFT27 24234451 25348397 27173435 association anti tag coimmunoprecipitation ComPPI,IntAct
NME3 SGTB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NME3 UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NME3 DESI1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NME3 HSCB 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
NME3 COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NME3 PLGRKT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NME3 SFXN1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NME3 TOMM20 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NME3 TOMM22 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NME3 TUBA1A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NME3 OCIAD1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NME3 NDUFAF8 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
MGST3 NME3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NME3 NME3 11042679 14525934 N/A experimental interaction detection HPRD
SRC NME3 11042679 27898060 N/A N/A OmniPath

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