GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
NUBPL
FullNmae
NUBP iron-sulfur cluster assembly factor, mitochondrial
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:20278
EnsembleID
ENSG00000151413
Uniprot
Q8TB37
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
NUBPL
immunogenic
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
NUBPL
autosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
NUBPL
cuproptosis
36313717
The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in聽Table S1.
Genes of iron-sulfur cluster related proteins
NUBPL
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
NUBPL
GO:0005515,GO:0005524,GO:0005739,GO:0005739,GO:0005759,GO:0005886,GO:0016226,GO:0032981,GO:0032981,GO:0046872,GO:0051539,GO:0051539,GO:0070584,GO:0140663
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
NUBPL
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
GATA2
NUBPL
18971253
19941826
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
GATA3
NUBPL
21878914
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
FOXA1
NUBPL
18971253
21878914
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
YBX1
NUBPL
19151767
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
SMARCA4
NUBPL
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
NUBPL
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
NUBPL
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
NUBPL
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
NUBPL
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
NUBPL
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
MITF
NUBPL
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
PRDM14
NUBPL
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
TAL1
NUBPL
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS000009262D
NUBPL
18591254
25416803
mrna cleavage,inhibition
array technology
TarBase
URS0000122F23
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000008A99
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000204177
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000600E6
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000075B538
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000451A1
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000024DFCE
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000F4AC3
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000020579D
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00005651EE
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002D349B
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000913AC
NUBPL
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
PPP1CA
NUBPL
24234451
25348397
25593058
association
anti bait coimmunoprecipitation
ComPPI,IntAct
RNF2
NUBPL
25348397
N/A
physical interaction
ComPPI
DNAJB11
NUBPL
25348397
N/A
physical interaction
ComPPI
UFD1
NUBPL
25348397
N/A
physical interaction
ComPPI
MTUS2
NUBPL
25348397
N/A
physical interaction
ComPPI
Visualization