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GENE：PIGN

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PIGN
FullNmae phosphatidylinositol glycan anchor biosynthesis class N
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8967
EnsembleID ENSG00000197563
Uniprot O95427

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PIGN ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PIGN autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PIGN GO:0005789,GO:0005789,GO:0005829,GO:0005886,GO:0006506,GO:0016020,GO:0016254,GO:0051377,GO:0051377

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PIGN hsa:23556 path:hsa00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis - Homo sapiens (human)
PIGN hsa:23556 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
UNC93B1 PIGN 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PIGN 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PIGN 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PIGN 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PIGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PIGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PIGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PIGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PIGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PIGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PIGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PIGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 PIGN 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D PIGN 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS000000B1C9 PIGN 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D8730 PIGN 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000306C70 PIGN 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039D790 PIGN 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
YIPF3 PIGN 25348397 N/A physical interaction ComPPI
PTGIR PIGN 25348397 N/A physical interaction ComPPI
ATP2B2 PIGN 25348397 N/A physical interaction ComPPI
VIPR2 PIGN 25348397 N/A physical interaction ComPPI
ELAVL1 PIGN 25348397 N/A physical interaction ComPPI
SHMT2 PIGN 25348397 N/A physical interaction ComPPI
FPR2 PIGN 25348397 N/A physical interaction ComPPI
NXF1 PIGN 25348397 N/A physical interaction ComPPI
MOV10 PIGN 25348397 N/A physical interaction ComPPI
UNC93B1 PIGN 25348397 N/A physical interaction ComPPI
PIGN FJX1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PIGN TXNDC15 25348397 N/A physical interaction ComPPI
PIGN SPPL2B 25348397 N/A physical interaction ComPPI
PIGN GPR21 25348397 N/A physical interaction ComPPI
PIGN TMEM63A 25348397 N/A physical interaction ComPPI

Visualization










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