GENE:RHOQ
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RHOQ |
| FullNmae | ras homolog family member Q |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17736 |
| EnsembleID | ENSG00000119729 |
| Uniprot | P17081 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RHOQ | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RHOQ | GO:0003924,GO:0003924,GO:0005515,GO:0005522,GO:0005525,GO:0005884,GO:0005886,GO:0005886,GO:0005886,GO:0006897,GO:0007015,GO:0007163,GO:0007165,GO:0007264,GO:0008286,GO:0008360,GO:0019901,GO:0030660,GO:0030866,GO:0030866,GO:0032427,GO:0032869,GO:0032956,GO:0045121,GO:0045944,GO:0046039,GO:0046326,GO:0051491,GO:0070062,GO:1903077 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| RHOQ | hsa:23433 | path:hsa04910 | Insulin signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | RHOQ | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | RHOQ | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | RHOQ | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | RHOQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | RHOQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RHOQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | RHOQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RHOQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | RHOQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | RHOQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | RHOQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | RHOQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | RHOQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | RHOQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | RHOQ | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000ED600 | RHOQ | 20215506 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000009262D | RHOQ | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000003ABC4 | RHOQ | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AF715 | RHOQ | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032BD73 | RHOQ | 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000046CDA6 | RHOQ | 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | RHOQ | 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | RHOQ | 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PARD6A | RHOQ | 25361965 | interaction type | N/A | PTMCode2 |
| RHOQ | PARD6A | 25361965 | interaction type | N/A | PTMCode2 |
| RHOQ | CDC42EP1 | 25361965 | interaction type | N/A | PTMCode2 |
| CDC42EP1 | RHOQ | 25361965 | interaction type | N/A | PTMCode2 |
| RHOQ | CDC42EP2 | 25361965 | interaction type | N/A | PTMCode2 |
| CDC42EP2 | RHOQ | 25361965 | interaction type | N/A | PTMCode2 |
| RHOQ | CDC42EP3 | 25361965 | interaction type | N/A | PTMCode2 |
| CDC42EP3 | RHOQ | 25361965 | interaction type | N/A | PTMCode2 |
| RHOQ | PRKCI | 25361965 | interaction type | N/A | PTMCode2 |
| PRKCI | RHOQ | 25361965 | interaction type | N/A | PTMCode2 |
| RHOQ | ARHGAP1 | 25361965 | interaction type | N/A | PTMCode2 |
| ARHGAP1 | RHOQ | 25361965 | interaction type | N/A | PTMCode2 |
| RHOQ | CDC42EP4 | 25361965 | interaction type | N/A | PTMCode2 |
| CDC42EP4 | RHOQ | 25361965 | interaction type | N/A | PTMCode2 |
| RHOQ | GOPC | 25361965 | interaction type | N/A | PTMCode2 |
| GOPC | RHOQ | 25361965 | interaction type | N/A | PTMCode2 |
| RHOQ | PARD6B | 25361965 | interaction type | N/A | PTMCode2 |
| PARD6B | RHOQ | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| WASL | RHOQ | 12456725 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD,OmniPath |
| CDC42EP2 | RHOQ | 10490598 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
| WAS | RHOQ | 14521508 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| RHOQ | PFN1 | 10445846 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD,OmniPath |
| RHOQ | COPB1 | 12134073 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| RHOQ | TRIP10 | 12242347 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| RHOQ | GOPC | 11162552 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| RHOQ | PARD6A | 10934474 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
| RHOQ | CDC42EP1 | 10490598 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD |
| RHOQ | CDC42EP4 | 10490598 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD |
| RHOQ | CDC42EP3 | 10490598 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
| RHOQ | COPG1 | 12134073 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| RHOQ | DOCK8 | 14525934 15304341 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| RHOQ | PARD6B | 10934474 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
| RHOQ | RAPGEF1 | 11309621 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| RHOQ | EXOC7 | 12687004 14525934 25348397 | N/A | experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD |
| RHOQ | CDC42BPG | 15194684 24234451 25348397 | physical association | far western blotting,physical interaction | ComPPI,IntAct |
| RHOQ | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| RHOQ | TRIP6 | 25348397 | N/A | physical interaction | ComPPI |
| RHOQ | CDC42BPA | 15194684 24234451 25348397 | physical association | far western blotting | ComPPI,IntAct |
| RHOQ | PAK1 | 25348397 | N/A | pull down | ComPPI |
| RHOQ | ZNF417 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PRKCI | RHOQ | 10934474 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| FADD | RHOQ | 24234451 30561431 | association | virotrap | IntAct |
| RHOQ | PAK1 | 27898060 9799731 | stimulant | N/A | OmniPath |
| RHOQ | EXOC7 | 12687004 27898060 | stimulant | N/A | OmniPath |
