GENE：TSC22D2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TSC22D2 |
| FullNmae | TSC22 domain family member 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29095 |
| EnsembleID | ENSG00000196428 |
| Uniprot | O75157 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TSC22D2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TSC22D2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TSC22D2 | cuproptosis | 36010978 | Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. | Cuproptosis-related genes |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TSC22D2 | GO:0006357,GO:0006970 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TSC22D2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | TSC22D2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | TSC22D2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | TSC22D2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | TSC22D2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000ED600 | TSC22D2 | 20215506 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000122ED0 | TSC22D2 | 19088304 23592263 24398324 25416803 | mrna cleavage,inhibition | array technology,clip | TarBase |
| URS000003ABC4 | TSC22D2 | 19088304 21572407 25416803 | mrna cleavage,inhibition | array technology,clip | TarBase |
| URS00006DE17B | TSC22D2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003CF1AD | TSC22D2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000170CF4 | TSC22D2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003E6EFA | TSC22D2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000036B845 | TSC22D2 | 21572407 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BEA7 | TSC22D2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DA9DB | TSC22D2 | 20371350 22100165 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000044FD7 | TSC22D2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029D9F1 | TSC22D2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000083D87 | TSC22D2 | 22100165 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000049FAE8 | TSC22D2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016D2D4 | TSC22D2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075ABF4 | TSC22D2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D8730 | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000025EABA | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043D2C1 | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008AA34 | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000118224 | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000015188E | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CE0C6 | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000B1C9 | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000324096 | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000031E12 | TSC22D2 | 23592263 24398324 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A07C1 | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029979D | TSC22D2 | 23592263 24398324 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000032EF64 | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237CBD | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000821E0 | TSC22D2 | 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004900F1 | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AF45F | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000042E8CC | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000272A92 | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039607D | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000250A40 | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E1509 | TSC22D2 | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021D7C8 | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CF3F0 | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000024B619 | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000050CCE0 | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077AED | TSC22D2 | 23592263 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F6E49 | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | TSC22D2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AF715 | TSC22D2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037E170 | TSC22D2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040828B | TSC22D2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012930C | TSC22D2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD02D | TSC22D2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EE123 | TSC22D2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F24A9 | TSC22D2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000FC8EB | TSC22D2 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008F0CF | TSC22D2 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000482389 | TSC22D2 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029D793 | TSC22D2 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CF056 | TSC22D2 | 24906430 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000ECE9C | TSC22D2 | 24906430 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BCD9C | TSC22D2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E92A8 | TSC22D2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003804D8 | TSC22D2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | TSC22D2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F859B | TSC22D2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D6C3F | TSC22D2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000136174 | TSC22D2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000239117 | TSC22D2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D0874 | TSC22D2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | TSC22D2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000034979B | TSC22D2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000353492 | TSC22D2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003808EC | TSC22D2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000157F5 | TSC22D2 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B7E30 | TSC22D2 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SAP18 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| MSH3 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| KEAP1 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| MPDZ | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| TSC22D3 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| TTN | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| F8 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| LPL | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| WDR77 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| ATP1B1 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| RNF2 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| ITGA2 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| FLNB | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| MED13 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| ZMYM2 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| STK39 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| NRBP1 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| PSMA7 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| PRMT3 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| REV1 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| TSC22D4 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| ARID2 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| RBL1 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| SCEL | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| UFM1 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| CLIP1 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF143 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| TMA7 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| WNK3 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |