Gene Information gene info

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GENE：NSMCE4A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NSMCE4A
FullNmae NSE4 homolog A, SMC5-SMC6 complex component
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25935
EnsembleID ENSG00000107672
Uniprot Q9NXX6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NSMCE4A parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NSMCE4A GO:0000724,GO:0000781,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006281,GO:0006974,GO:0016604,GO:0016925,GO:0030915,GO:0030915,GO:0030915,GO:0032204,GO:0140588

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SRPK1 NSMCE4A 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 NSMCE4A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 NSMCE4A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NSMCE4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NSMCE4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NSMCE4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NSMCE4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NSMCE4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NSMCE4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NSMCE4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NSMCE4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 NSMCE4A 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
MAGEA1 NSMCE4A 21364888 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 NSMCE4A 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
MAGEH1 NSMCE4A 25348397 N/A physical interaction ComPPI
MAGEC2 NSMCE4A 25348397 N/A physical interaction ComPPI
DNAJB2 NSMCE4A 25348397 N/A physical interaction ComPPI
PPARD NSMCE4A 25348397 N/A physical interaction ComPPI
BRCA2 NSMCE4A 25348397 N/A physical interaction ComPPI
SRPK1 NSMCE4A 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
NDN NSMCE4A 21364888 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPB1 NSMCE4A 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
PJA1 NSMCE4A 25348397 N/A physical interaction ComPPI
TUFT1 NSMCE4A 25348397 N/A physical interaction ComPPI
SRPK2 NSMCE4A 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
BRCA1 NSMCE4A 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
TRIM31 NSMCE4A 25348397 N/A physical interaction ComPPI
ARNTL2 NSMCE4A 25348397 N/A physical interaction ComPPI
HECW2 NSMCE4A 25348397 N/A physical interaction ComPPI
L3MBTL1 NSMCE4A 25348397 N/A physical interaction ComPPI
TULP2 NSMCE4A 25348397 N/A physical interaction ComPPI
SIRT6 NSMCE4A 25348397 N/A physical interaction ComPPI
AKT2 NSMCE4A 25348397 N/A physical interaction ComPPI
MAGED2 NSMCE4A 25348397 N/A physical interaction ComPPI
MAGED4 NSMCE4A 21364888 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NSMCE3 NSMCE4A 20864041 21364888 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
SMC5 NSMCE4A 25348397 N/A physical interaction ComPPI
SMC6 NSMCE4A 18086888 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IER2 NSMCE4A 25348397 N/A physical interaction ComPPI
MAGEB1 NSMCE4A 25348397 N/A physical interaction ComPPI
NSMCE1 NSMCE4A 18086888 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,physical interaction ComPPI,IntAct
NSMCE4A ODAD3 25348397 N/A physical interaction ComPPI
NSMCE4A TSPYL6 25348397 N/A physical interaction ComPPI
NSMCE4A C6ORF141 25348397 N/A physical interaction ComPPI
ZNF597 NSMCE4A 25348397 N/A physical interaction ComPPI

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