GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
EPS8L2 |
FullNmae |
EPS8 signaling adaptor L2 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:21296 |
EnsembleID |
ENSG00000177106 |
Uniprot |
Q9H6S3 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
EPS8L2 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
EPS8L2 |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
EPS8L2 |
GO:0003779,GO:0003779,GO:0005085,GO:0005515,GO:0005813,GO:0005829,GO:0005886,GO:0007266,GO:0007266,GO:0007605,GO:0031982,GO:0032421,GO:0032426,GO:0032587,GO:0032587,GO:0032991,GO:0035023,GO:0035023,GO:0045296,GO:0070062,GO:1900029,GO:1900029 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
SMARCA4 |
EPS8L2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
EPS8L2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
EPS8L2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
EPS8L2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
EPS8L2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXP1 |
EPS8L2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
EPS8L2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
EPS8L2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
MITF |
EPS8L2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TP53 |
EPS8L2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00000EED18 |
EPS8L2 |
21566225
25416803
|
mrna cleavage,inhibition |
experimental interaction detection |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
EPS8L2 |
ABI1 |
25361965
|
interaction type |
N/A |
PTMCode2 |
ABI1 |
EPS8L2 |
25361965
|
interaction type |
N/A |
PTMCode2 |
EPS8L2 |
SOS1 |
25361965
|
interaction type |
N/A |
PTMCode2 |
SOS1 |
EPS8L2 |
25361965
|
interaction type |
N/A |
PTMCode2 |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
SNW1 |
EPS8L2 |
20467437
24234451
25348397
|
association |
anti bait coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
CDC5L |
EPS8L2 |
20467437
24234451
25348397
|
association |
anti bait coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
ACTG1 |
EPS8L2 |
25348397
|
N/A |
physical interaction |
ComPPI |
SOS1 |
EPS8L2 |
25348397
|
N/A |
physical interaction,in vitro |
ComPPI |
CD3E |
EPS8L2 |
17617578
24234451
25348397
|
physical association |
filamentous phage display |
ComPPI,IntAct |
CDH1 |
EPS8L2 |
25348397
|
N/A |
physical interaction |
ComPPI |
TNS2 |
EPS8L2 |
24234451
25348397
25814554
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
NAXE |
EPS8L2 |
25348397
|
N/A |
physical interaction |
ComPPI |
RIN3 |
EPS8L2 |
24234451
25348397
25814554
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
XPO1 |
EPS8L2 |
25348397
|
N/A |
physical interaction |
ComPPI |
ABI1 |
EPS8L2 |
25348397
|
N/A |
physical interaction |
ComPPI |
RPL23 |
EPS8L2 |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
EPS8L2 |
PTK2 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
EPS8L2 |
APP |
25348397
|
N/A |
physical interaction |
ComPPI |
EPS8L2 |
ASTE1 |
25348397
|
N/A |
physical interaction |
ComPPI |
EPS8L2 |
LRRK2 |
24234451
24947832
25348397
|
N/A |
protein array |
ComPPI,IntAct |
EPS8L2 |
PLEKHA7 |
24234451
25348397
28877994
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
Visualization