Gene Information gene info

GENE:EPS8L2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EPS8L2
FullNmae EPS8 signaling adaptor L2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21296
EnsembleID ENSG00000177106
Uniprot Q9H6S3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EPS8L2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EPS8L2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EPS8L2 GO:0003779,GO:0003779,GO:0005085,GO:0005515,GO:0005813,GO:0005829,GO:0005886,GO:0007266,GO:0007266,GO:0007605,GO:0031982,GO:0032421,GO:0032426,GO:0032587,GO:0032587,GO:0032991,GO:0035023,GO:0035023,GO:0045296,GO:0070062,GO:1900029,GO:1900029

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 EPS8L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EPS8L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EPS8L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EPS8L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EPS8L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 EPS8L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EPS8L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EPS8L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EPS8L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 EPS8L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 EPS8L2 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
EPS8L2 ABI1 25361965 interaction type N/A PTMCode2
ABI1 EPS8L2 25361965 interaction type N/A PTMCode2
EPS8L2 SOS1 25361965 interaction type N/A PTMCode2
SOS1 EPS8L2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 EPS8L2 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L EPS8L2 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTG1 EPS8L2 25348397 N/A physical interaction ComPPI
SOS1 EPS8L2 25348397 N/A physical interaction,in vitro ComPPI
CD3E EPS8L2 17617578 24234451 25348397 physical association filamentous phage display ComPPI,IntAct
CDH1 EPS8L2 25348397 N/A physical interaction ComPPI
TNS2 EPS8L2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NAXE EPS8L2 25348397 N/A physical interaction ComPPI
RIN3 EPS8L2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
XPO1 EPS8L2 25348397 N/A physical interaction ComPPI
ABI1 EPS8L2 25348397 N/A physical interaction ComPPI
RPL23 EPS8L2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EPS8L2 PTK2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EPS8L2 APP 25348397 N/A physical interaction ComPPI
EPS8L2 ASTE1 25348397 N/A physical interaction ComPPI
EPS8L2 LRRK2 24234451 24947832 25348397 N/A protein array ComPPI,IntAct
EPS8L2 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct

Visualization