Gene Information gene info

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GENE：WAPL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol WAPL
FullNmae WAPL cohesin release factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23293
EnsembleID ENSG00000062650
Uniprot Q7Z5K2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
WAPL mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WAPL autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
WAPL GO:0000070,GO:0000775,GO:0000785,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005694,GO:0005737,GO:0005829,GO:0005829,GO:0008156,GO:0035562,GO:0043231,GO:0045171,GO:0045875,GO:0051301,GO:0071168,GO:0071922,GO:0072686,GO:0140083

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
WAPL hsa:23063 path:hsa04110 Cell cycle - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
WAPL POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 WAPL 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 WAPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA WAPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF WAPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 WAPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 WAPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS WAPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A WAPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 WAPL N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003BBF48 WAPL 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000AA464 WAPL 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F WAPL 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 WAPL 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B WAPL 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 WAPL 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003804D8 WAPL 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003538C1 WAPL 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 WAPL 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 WAPL 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNW1 WAPL 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NSMCE2 WAPL 25348397 N/A physical interaction ComPPI
VCP WAPL 25348397 N/A physical interaction ComPPI
FOXB1 WAPL 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RAD21 WAPL 17112726 17113138 20360068 24234451 25173175 25348397 26496610 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cosedimentation through density gradient,pull down,physical interaction,in vivo,tandem affinity purification ComPPI,IntAct
KEAP1 WAPL 25348397 N/A physical interaction ComPPI
EGLN3 WAPL 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL10 WAPL 25348397 N/A physical interaction ComPPI
NTRK1 WAPL 25348397 N/A physical interaction ComPPI
RPA1 WAPL 25348397 N/A physical interaction ComPPI
STAG1 WAPL 17112726 17113138 20360068 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
MAPK6 WAPL 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
RPA2 WAPL 25348397 N/A physical interaction ComPPI
RPA3 WAPL 25348397 N/A physical interaction ComPPI
SMC1A WAPL 17112726 17113138 20360068 23242214 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CDK7 WAPL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SMC3 WAPL 17112726 17113138 17349791 20360068 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
AURKA WAPL 25348397 N/A physical interaction ComPPI
CDK8 WAPL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
H3C1 WAPL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
XRN1 WAPL 15231747 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FOXH1 WAPL 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MTNR1A WAPL 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
ELAVL1 WAPL 25348397 N/A physical interaction ComPPI
DYNLT1 WAPL 25348397 N/A physical interaction ComPPI
BRCA1 WAPL 25348397 N/A physical interaction ComPPI
UPF3A WAPL 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VPS16 WAPL 25348397 N/A physical interaction ComPPI
STAG2 WAPL 17112726 17113138 20360068 24234451 25173175 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
PFDN2 WAPL 25348397 N/A physical interaction ComPPI
SRRM1 WAPL 25348397 N/A physical interaction ComPPI
USP10 WAPL 25348397 N/A physical interaction ComPPI
RUVBL2 WAPL 25348397 N/A physical interaction ComPPI
WAPL PDS5A 17112726 17113138 20360068 21111234 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
WAPL PDS5B 17112726 17113138 20360068 24234451 25348397 association,physical association anti bait coimmunoprecipitation,cosedimentation,physical interaction,tandem affinity purification ComPPI,IntAct
WAPL ARAP1 25348397 N/A physical interaction ComPPI
WAPL USP15 25348397 N/A physical interaction ComPPI
WAPL WRAP53 25348397 N/A physical interaction ComPPI
WAPL SIRT6 25348397 N/A physical interaction ComPPI
WAPL SCCPDH 25348397 N/A physical interaction ComPPI
WAPL NDUFA8 25348397 N/A physical interaction ComPPI
WAPL TTC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WAPL CDCA5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WAPL ATG2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WAPL EPB41L4B 25348397 N/A physical interaction ComPPI
WAPL ZSWIM9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WAPL FOXI2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
WAPL USP37 25348397 N/A physical interaction ComPPI
WAPL DEFA5 25348397 N/A physical interaction ComPPI
WAPL ST6GAL1 25348397 N/A physical interaction ComPPI
WAPL DNAJC10 25348397 N/A physical interaction ComPPI
WAPL TULP3 25348397 N/A physical interaction ComPPI
WAPL SLCO1B1 25348397 N/A physical interaction ComPPI
WAPL SGO1 23242214 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WAPL TCTE1 24234451 25348397 26638075 association proximity-dependent biotin identification ComPPI,IntAct
COMTD1 WAPL 25348397 N/A physical interaction ComPPI
WAPL WAPL 20360068 24234451 physical association tandem affinity purification IntAct
XRCC6 WAPL 24234451 30021884 physical association cross-linking study IntAct
WAPL RAD21 17112726 17113138 20360068 22145905 26496610 27898060 inhibition N/A OmniPath

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