GENE：TMCC1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TMCC1 |
| FullNmae | transmembrane and coiled-coil domain family 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29116 |
| EnsembleID | ENSG00000172765 |
| Uniprot | O94876 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TMCC1 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TMCC1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TMCC1 | GO:0005515,GO:0005789,GO:0005791,GO:0005829,GO:0007029,GO:0012505,GO:0016197,GO:0016197,GO:0042802,GO:0090148,GO:0090148,GO:0097750,GO:0097750,GO:0140284,GO:0140285,GO:0140285 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TMCC1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | TMCC1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | TMCC1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | TMCC1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | TMCC1 | 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | TMCC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00002C02E4 | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003BF62 | TMCC1 | 20371350 21572407 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000018C928 | TMCC1 | 20371350 21572407 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000236310 | TMCC1 | 20371350 21572407 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005C1F22 | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D15B | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032D69B | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000058DCD8 | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000045E0EC | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EB9FC | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000049FAE8 | TMCC1 | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00003808EC | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000101787 | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005481D | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000153377 | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170CF4 | TMCC1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003ABC4 | TMCC1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HNRNPL | TMCC1 | 25348397 | N/A | physical interaction | ComPPI |
| ZDHHC17 | TMCC1 | 24234451 24705354 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| APP | TMCC1 | 25348397 | N/A | physical interaction | ComPPI |
| TMCC1 | ARHGEF4 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| CBX5 | TMCC1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009AFCC2 | TMCC1 | 27087310 | direct interaction,inhibition | N/A | NPInter |