GENE:N4BP1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | N4BP1 |
| FullNmae | NEDD4 binding protein 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29850 |
| EnsembleID | ENSG00000102921 |
| Uniprot | O75113 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| N4BP1 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| N4BP1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| N4BP1 | GO:0001818,GO:0003729,GO:0004540,GO:0005515,GO:0005634,GO:0005730,GO:0005829,GO:0005829,GO:0016605,GO:0016605,GO:0031397,GO:0031397,GO:0032435,GO:0032435,GO:0034644,GO:0043130,GO:0045071,GO:0045087,GO:0045088 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| N4BP1 | ITCH | 17592138 23180781 | physical association | anti tag coimmunoprecipitation,pull down | InnateDB |
| N4BP1 | UBC | 19285159 23180781 | physical association | protein array,pull down | InnateDB |
| AZI2 | N4BP1 | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | N4BP1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | N4BP1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | N4BP1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | N4BP1 | 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| YBX1 | N4BP1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | N4BP1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | N4BP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | N4BP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | N4BP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | N4BP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | N4BP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | N4BP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | N4BP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | N4BP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | N4BP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | N4BP1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F2 | N4BP1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000016C318 | N4BP1 | 20445018 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
| URS00001799A3 | N4BP1 | 20445018 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
| URS000019D79B | N4BP1 | 20445018 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
| URS00001799A3 | N4BP1 | 20445018 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS000019D79B | N4BP1 | 20445018 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS000016C318 | N4BP1 | 20445018 22928040 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00000DDD35 | N4BP1 | 22473208 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS00004719AB | N4BP1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | N4BP1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000338542 | N4BP1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | N4BP1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | N4BP1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000010BD8D | N4BP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D814 | N4BP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075CC78 | N4BP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | N4BP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000100748 | N4BP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FC5B0 | N4BP1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F6E49 | N4BP1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | N4BP1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | N4BP1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | N4BP1 | 20371350 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | N4BP1 | 20371350 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | N4BP1 | 20371350 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008F0CF | N4BP1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | N4BP1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | N4BP1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | N4BP1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | N4BP1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000568FF8 | N4BP1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000017CCCB | N4BP1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FFA8C | N4BP1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000023F008 | N4BP1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000054A671 | N4BP1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000284586 | N4BP1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDK6 | N4BP1 | 22094256 24234451 25348397 | phosphorylation reaction | physical interaction,protein kinase assay | ComPPI,IntAct |
| LSM1 | N4BP1 | 25348397 | N/A | physical interaction | ComPPI |
| CUL3 | N4BP1 | 25348397 | N/A | physical interaction | ComPPI |
| UBC | N4BP1 | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | N4BP1 | 25348397 | N/A | physical interaction | ComPPI |
| ITCH | N4BP1 | 17592138 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
| MID1 | N4BP1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| LITAF | N4BP1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AZI2 | N4BP1 | 25348397 | N/A | physical interaction | ComPPI |
| HYPK | N4BP1 | 25348397 | N/A | physical interaction | ComPPI |
| N4BP1 | FAM114A1 | 25348397 | N/A | physical interaction | ComPPI |
| AZI2 | N4BP1 | 21903422 27898060 | N/A | N/A | OmniPath |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009B52C3 | N4BP1 | 27087310 | direct interaction,inhibition | N/A | NPInter |
