Gene Information gene info

GENE:SPSB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPSB1
FullNmae splA/ryanodine receptor domain and SOCS box containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30628
EnsembleID ENSG00000171621
Uniprot Q96BD6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPSB1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPSB1 GO:0005515,GO:0005829,GO:0005829,GO:0006511,GO:0016567,GO:0016567,GO:0019005,GO:0043161,GO:1990756

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ELOC SPSB1 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
ELOB SPSB1 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
RNF7 SPSB1 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
CUL5 SPSB1 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
SPSB1 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR SPSB1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SPSB1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SPSB1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SPSB1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C SPSB1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA SPSB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPSB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SPSB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SPSB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SPSB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SPSB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SPSB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SPSB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SPSB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SPSB1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000048BA36 SPSB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A SPSB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 SPSB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F SPSB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000192A75 SPSB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 SPSB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D SPSB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB SPSB1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 SPSB1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 SPSB1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 SPSB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000019907A SPSB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000137EDE SPSB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A9CF SPSB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F9738 SPSB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122F23 SPSB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002CBC6D SPSB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000021D08 SPSB1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MET SPSB1 25361965 interaction type N/A PTMCode2
SPSB1 MET 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 SPSB1 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SNAI1 SPSB1 24234451 25203322 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
HSP90AB1 SPSB1 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
RNF7 SPSB1 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TGFBR2 SPSB1 25348397 N/A physical interaction ComPPI
HSP90AA1 SPSB1 25348397 N/A physical interaction ComPPI
PRMT1 SPSB1 23455924 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
HNRNPL SPSB1 25348397 N/A physical interaction ComPPI
TP73 SPSB1 25348397 N/A physical interaction ComPPI
PAWR SPSB1 20561531 24234451 25348397 N/A isothermal titration calorimetry,x-ray crystallography,physical interaction ComPPI,IntAct
ATM SPSB1 25348397 N/A physical interaction ComPPI
SUV39H1 SPSB1 23455924 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
MET SPSB1 14525934 15713673 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RASA1 SPSB1 14525934 15713673 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NOS2 SPSB1 25348397 N/A physical interaction ComPPI
ELOB SPSB1 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELOC SPSB1 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELAVL1 SPSB1 25348397 N/A physical interaction ComPPI
KDM1A SPSB1 23455924 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
DDX4 SPSB1 25348397 N/A physical interaction ComPPI
SPSB1 TP53 25348397 N/A physical interaction ComPPI
SPSB1 HSP90AA2P 25348397 N/A physical interaction ComPPI
SPSB1 PRMT6 23455924 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
SPSB1 VWA5A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ADPRH SPSB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPSB1 VAS 20561531 24234451 N/A isothermal titration calorimetry,x-ray crystallography IntAct
MET SPSB1 15713673 27898060 N/A N/A OmniPath

Visualization