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GENE：POLR1A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol POLR1A
FullNmae RNA polymerase I subunit A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17264
EnsembleID ENSG00000068654
Uniprot O95602

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
POLR1A parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
POLR1A mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
POLR1A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
POLR1A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
POLR1A GO:0001054,GO:0003677,GO:0003682,GO:0003899,GO:0005515,GO:0005654,GO:0005694,GO:0005736,GO:0006360,GO:0046872,GO:1904750

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
POLR1A hsa:25885 path:hsa03020 RNA polymerase - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 POLR1A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR POLR1A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 POLR1A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 POLR1A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 POLR1A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 POLR1A 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 POLR1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA POLR1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF POLR1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 POLR1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 POLR1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 POLR1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS POLR1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A POLR1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF POLR1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 POLR1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 POLR1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 POLR1A 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003D5391 POLR1A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000020579D POLR1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 POLR1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 POLR1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF POLR1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 POLR1A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A9CF POLR1A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 POLR1A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003FBC84 POLR1A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003AA845 POLR1A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000006372A POLR1A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041FA2C POLR1A 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ANP32B POLR1A 14525934 25348397 27898060 9285060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
RPL9 POLR1A 25348397 N/A physical interaction ComPPI
POLR2L POLR1A 19214185 24234451 25348397 association chromatography technology,physical interaction ComPPI,IntAct
RARA POLR1A 24234451 25303530 25348397 association pull down ComPPI,IntAct
POLR3C POLR1A 25348397 N/A physical interaction ComPPI
POLR1A NOLC1 10567578 25348397 27898060 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
POLR1A RRN3 11250903 14525934 19214185 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
POLR1A POLR1E 14525934 15226435 19214185 24234451 25348397 association experimental interaction detection,chromatography technology,physical interaction,in vitro ComPPI,HPRD,IntAct
POLR1A NFKBIB 14525934 14743216 24234451 25348397 physical association experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
POLR1A POLR1G 19214185 24234451 25348397 26496610 association anti tag coimmunoprecipitation,chromatography technology,physical interaction ComPPI,IntAct
POLR1A TAF1D 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A USP11 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A RPAP3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A TAF13 25348397 N/A physical interaction ComPPI
POLR1A POLR1B 16514417 19214185 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,chromatography technology,physical interaction ComPPI,IntAct
POLR1A SSRP1 19214185 24234451 25348397 association chromatography technology,physical interaction ComPPI,IntAct
POLR1A POLR1C 19214185 24234451 25348397 26496610 association anti tag coimmunoprecipitation,chromatography technology,physical interaction ComPPI,IntAct
POLR1A POLR2E 19214185 24234451 25348397 26496610 association anti tag coimmunoprecipitation,chromatography technology,physical interaction ComPPI,IntAct
POLR1A POLR2H 19214185 24234451 25348397 association chromatography technology,physical interaction ComPPI,IntAct
POLR1A SUPT16H 19214185 24234451 25348397 association chromatography technology,physical interaction ComPPI,IntAct
POLR1A SIRT7 25348397 N/A physical interaction ComPPI
POLR1A ERCC6 25348397 N/A physical interaction ComPPI
POLR1A ERCC6 25348397 N/A physical interaction ComPPI
POLR1A UBTF 25348397 N/A physical interaction ComPPI
POLR1A MYBBP1A 25348397 N/A physical interaction ComPPI
POLR1A SMARCA5 25348397 N/A physical interaction ComPPI
POLR1A ARRB1 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A ARRB2 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A POLR1D 25348397 N/A physical interaction ComPPI
POLR1A POLR1D 19214185 24234451 25348397 26496610 association anti tag coimmunoprecipitation,chromatography technology,physical interaction ComPPI,IntAct
POLR1A POLR3A 25348397 N/A physical interaction ComPPI
POLR1A INO80 25348397 N/A physical interaction ComPPI
POLR1A LGR4 25348397 N/A physical interaction ComPPI
POLR1A REL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
POLR1A TCF4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
POLR1A ENO1 25348397 N/A physical interaction ComPPI
POLR1A SHMT2 25348397 N/A physical interaction ComPPI
POLR1A MOV10 25348397 N/A physical interaction ComPPI
POLR1A NXF1 25348397 N/A physical interaction ComPPI
POLR1A KAT2B 25348397 N/A physical interaction ComPPI
POLR1A CCDC8 25348397 N/A physical interaction ComPPI
POLR1A RNF2 25348397 N/A physical interaction ComPPI
POLR1A GPN3 25348397 N/A physical interaction ComPPI
POLR1A PIH1D1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A POLR1F 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A SCP2 25348397 N/A physical interaction ComPPI
POLR1A SKAP1 25348397 N/A physical interaction ComPPI
POLR1A GFOD1 25348397 N/A physical interaction ComPPI
POLR1A FBXW11 25348397 N/A physical interaction ComPPI
POLR1A EEF1A1 25348397 N/A physical interaction ComPPI
POLR1A EEF1A1P5 25348397 N/A physical interaction ComPPI
POLR1A EEF1A2 25348397 N/A physical interaction ComPPI
POLR1A POLR2B 25348397 N/A physical interaction ComPPI
POLR1A POLR2F 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A POLR3B 25348397 N/A physical interaction ComPPI
POLR1A RPS5 25348397 N/A physical interaction ComPPI
POLR1A RPL10A 25348397 N/A physical interaction ComPPI
POLR1A TRIP10 25348397 N/A physical interaction ComPPI
POLR1A DIAPH2 25348397 N/A physical interaction ComPPI
POLR1A PFDN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A POLR2K 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A SUPT6H 25348397 N/A physical interaction ComPPI
POLR1A RUVBL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A URI1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A TAF1C 25348397 N/A physical interaction ComPPI
POLR1A TAF1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A PFDN6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A RUVBL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A GPN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A L1TD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A POLR1H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A KIAA1522 25348397 N/A physical interaction ComPPI
POLR1A NCKAP5L 25348397 N/A physical interaction ComPPI
POLR1A PDRG1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A DNAAF10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1A TCOF1 25348397 N/A physical interaction ComPPI
POLR1A NOP58 25348397 N/A physical interaction ComPPI
POLR1A KBTBD8 25348397 N/A physical interaction ComPPI
POLR1A CSNK2A1 25348397 N/A physical interaction ComPPI
POLR1A RECQL5 25348397 N/A physical interaction ComPPI
POLR1A BRCA1 25348397 N/A physical interaction ComPPI
POLR1A UXT 25348397 N/A physical interaction ComPPI
POLR1A TENT5A 25348397 N/A physical interaction ComPPI
POLR1A ASB7 25348397 N/A physical interaction ComPPI
POLR1A LGALS13 25348397 N/A physical interaction ComPPI
POLR1A SNX21 25348397 N/A physical interaction ComPPI
POLR1A CDH5 25348397 N/A physical interaction ComPPI
POLR1A SHPRH 25348397 N/A physical interaction ComPPI
POLR1A ECD 25348397 N/A physical interaction ComPPI
POLR1A HNRNPL 25348397 N/A physical interaction ComPPI
POLR1A NBN 24234451 25064736 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
POLR1A AGO1 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
POLR1A BARD1 10477523 24234451 25348397 physical association pull down ComPPI,IntAct
POLR1A CSTF1 10477523 24234451 25348397 physical association pull down ComPPI,IntAct
POLR1A GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
POLR1A ERBB2 21555369 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,electron microscopy,confocal microscopy ComPPI,IntAct
POLR1A MAPK6 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
POLR1A DYDC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
POLR1A CDK7 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POLR1A FBL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRADD POLR1A 24234451 30561431 association virotrap IntAct
CLTA POLR1A 24234451 30021884 physical association cross-linking study IntAct

Visualization










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