Gene Information gene info

GENE:NUP58

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NUP58
FullNmae nucleoporin 58
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20261
EnsembleID ENSG00000139496
Uniprot Q9BVL2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NUP58 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NUP58 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NUP58 GO:0005515,GO:0005635,GO:0005635,GO:0005643,GO:0005643,GO:0006913,GO:0008139,GO:0015031,GO:0017056,GO:0031965,GO:0042306,GO:0042802,GO:0044877,GO:0051028

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NUP58 hsa:9818 path:hsa03013 Nucleocytoplasmic transport - Homo sapiens (human)
NUP58 hsa:9818 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 NUP58 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A NUP58 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 NUP58 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NUP58 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NUP58 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NUP58 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NUP58 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NUP58 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 NUP58 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 NUP58 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000508C13 NUP58 N/A 15685193 rna interference,inhibition array technology miRSponge
URS0000508C13 NUP58 15685193 25416803 mrna cleavage,inhibition array technology,array technology,experimental interaction detection TarBase
URS00000AA464 NUP58 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00000ED600 NUP58 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00000DDD35 NUP58 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000BE495 NUP58 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 NUP58 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004CD810 NUP58 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B NUP58 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 NUP58 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 NUP58 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 NUP58 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 NUP58 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000000E601 NUP58 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C NUP58 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 NUP58 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RNF40 NUP58 25348397 N/A physical interaction ComPPI
MEIS2 NUP58 25348397 N/A two hybrid ComPPI
NUP62 NUP58 11266456 14525934 21516116 24234451 25348397 25416956 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
VCP NUP58 25348397 N/A physical interaction ComPPI
KRT33B NUP58 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK3 NUP58 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CPNE2 NUP58 25348397 N/A physical interaction ComPPI
APC NUP58 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
LAMTOR3 NUP58 25348397 N/A physical interaction ComPPI
EEA1 NUP58 25348397 N/A physical interaction ComPPI
NUP98 NUP58 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
TRAF1 NUP58 24234451 25348397 25416956 27107012 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
UBQLN2 NUP58 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ABI3 NUP58 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HTT NUP58 17500595 23275563 24234451 25348397 physical association two hybrid,physical interaction,two hybrid prey pooling approach ComPPI,IntAct
RANBP2 NUP58 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPH1 NUP58 25348397 N/A physical interaction ComPPI
GOPC NUP58 25348397 N/A physical interaction ComPPI
UBQLN1 NUP58 25348397 N/A physical interaction ComPPI
NUP54 NUP58 24234451 25348397 25416956 26496610 30021884 association,physical association anti tag coimmunoprecipitation,cross-linking study,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PHF21A NUP58 25348397 N/A physical interaction ComPPI
PKNOX1 NUP58 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUP214 NUP58 25348397 N/A physical interaction ComPPI
NUP107 NUP58 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IFI16 NUP58 25348397 N/A physical interaction ComPPI
NUP58 ILF3 25348397 N/A physical interaction ComPPI
NUP58 TOMM40 25348397 N/A physical interaction ComPPI
NUP58 OBSL1 25348397 N/A physical interaction ComPPI
NUP58 SCLT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NUP58 DMD 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUP58 NUP93 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUP58 NUP205 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUP58 MIB2 25348397 N/A physical interaction ComPPI

Visualization