Gene Information gene info

GENE:UBTF

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBTF
FullNmae upstream binding transcription factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12511
EnsembleID ENSG00000108312
Uniprot P17480

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBTF autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UBTF GO:0001164,GO:0001164,GO:0001165,GO:0001181,GO:0001181,GO:0001188,GO:0001650,GO:0003682,GO:0003723,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005730,GO:0005730,GO:0006360,GO:0006360,GO:0006361,GO:0045943,GO:0045943,GO:0097110

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 UBTF 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 UBTF 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 UBTF 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 UBTF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UBTF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBTF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UBTF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UBTF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 UBTF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UBTF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UBTF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR UBTF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 UBTF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN UBTF N/A trascriptional regulation,stimulation inferred by curator TFlink
NFIC UBTF N/A trascriptional regulation,stimulation inferred by curator TFlink
SP1 UBTF N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A UBTF N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000512C88 UBTF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E UBTF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE UBTF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005FDE70 UBTF 23622248 25416803 26701625 mrna cleavage,inhibition clip,clash TarBase
URS000016D2D4 UBTF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001DABC0 UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F9738 UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 UBTF 21572407 23592263 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003E226A UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000014F13C UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004977C5 UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001919B0 UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 UBTF 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003380CC UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005485E8 UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000002103A UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5E03 UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 UBTF 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002F5FEE UBTF 21572407 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000046CDA6 UBTF 21572407 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000085F64 UBTF 21572407 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000076B539 UBTF 21572407 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00005E6F45 UBTF 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 UBTF 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 UBTF 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F UBTF 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004E02F2 UBTF 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BD6DC UBTF 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000004BACE UBTF 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000ECE9C UBTF 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004214BB UBTF 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000001A7A UBTF 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 UBTF 25361965 interaction type N/A PTMCode2
UBTF CSNK2A1 25361965 interaction type N/A PTMCode2
POLR1B UBTF 25361965 interaction type N/A PTMCode2
UBTF POLR1B 25361965 interaction type N/A PTMCode2
FBL UBTF 25361965 interaction type N/A PTMCode2
UBTF FBL 25361965 interaction type N/A PTMCode2
UBTF IRS1 25361965 interaction type N/A PTMCode2
IRS1 UBTF 25361965 interaction type N/A PTMCode2
UBTF TAF1D 25361965 interaction type N/A PTMCode2
TAF1D UBTF 25361965 interaction type N/A PTMCode2
UBTF TAF1A 25361965 interaction type N/A PTMCode2
TAF1A UBTF 25361965 interaction type N/A PTMCode2
UBTF SIRT7 25361965 interaction type N/A PTMCode2
SIRT7 UBTF 25361965 interaction type N/A PTMCode2
UBTF IRS2 25361965 interaction type N/A PTMCode2
IRS2 UBTF 25361965 interaction type N/A PTMCode2
UBTF POLR1E 25361965 interaction type N/A PTMCode2
POLR1E UBTF 25361965 interaction type N/A PTMCode2
UBTF MYC 25361965 interaction type N/A PTMCode2
MYC UBTF 25361965 interaction type N/A PTMCode2
UBTF TAF1C 25361965 interaction type N/A PTMCode2
TAF1C UBTF 25361965 interaction type N/A PTMCode2
TAF1B UBTF 25361965 interaction type N/A PTMCode2
UBTF TAF1B 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DAXX UBTF 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CTDSP2 UBTF 25348397 N/A physical interaction ComPPI
VIM UBTF 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCND1 UBTF 25348397 N/A physical interaction ComPPI
SET UBTF 17318177 24234451 25348397 physical association anti tag coimmunoprecipitation,far western blotting,pull down ComPPI,IntAct
LMNA UBTF 25348397 N/A physical interaction ComPPI
AP3M1 UBTF 25348397 N/A physical interaction ComPPI
TLE1 UBTF 20160071 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MAPK1 UBTF 11741541 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RPL10 UBTF 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TBP UBTF 14525934 25348397 27898060 8552083 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
MAPK3 UBTF 11741541 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RB1 UBTF 11042686 14525934 24234451 25348397 7877691 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
TAF1 UBTF 12498690 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
CREBBP UBTF 11106745 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RUNX2 UBTF 14525934 17251981 20160071 24234451 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
MYBBP1A UBTF 21297583 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
KAT2B UBTF 25348397 N/A physical interaction ComPPI
RAP1GDS1 UBTF 25348397 N/A physical interaction ComPPI
ACTN4 UBTF 25348397 N/A physical interaction ComPPI
UBTF POLR1G 14525934 25348397 27898060 9426281 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
UBTF RBL2 11042686 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
UBTF IRS2 12554758 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
UBTF SERPINH1 11106745 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
UBTF POLR1E 11592397 11698641 14525934 15226435 16582105 25348397 27898060 8641287 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
UBTF CSNK2A1 14525934 25348397 7651819 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
UBTF TCOF1 14525934 15249688 25348397 27898060 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,OmniPath
UBTF SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
UBTF CDK2 10202152 11698641 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
UBTF CENPC 14525934 25348397 27898060 8702533 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
UBTF MAD1L1 14525934 15282543 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
UBTF CCNA2 11698641 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
UBTF CHGB 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UBTF ZMYM2 14525934 15975576 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
UBTF IRS1 12554758 14525934 17332342 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
UBTF LEF1 12748295 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
UBTF TAF1C 25348397 N/A physical interaction ComPPI
UBTF RRN3 25348397 N/A physical interaction ComPPI
UBTF TAF1A 25348397 N/A physical interaction ComPPI
UBTF TAF1B 25348397 N/A physical interaction ComPPI
UBTF SIRT7 19174463 22147730 22586326 25348397 27898060 N/A physical interaction ComPPI,OmniPath
UBTF MCRS1 25348397 N/A physical interaction ComPPI
UBTF PIK3CA 25348397 N/A physical interaction ComPPI
UBTF CHD4 25348397 N/A physical interaction ComPPI
UBTF SMARCA5 25348397 N/A physical interaction ComPPI
UBTF KAT5 15016909 21668587 25348397 27898060 N/A physical interaction ComPPI,OmniPath
UBTF HDAC1 25348397 N/A physical interaction ComPPI
UBTF GRK5 25348397 N/A physical interaction ComPPI
UBTF WDR70 25348397 N/A physical interaction ComPPI
UBTF YEATS4 25348397 N/A physical interaction ComPPI
UBTF CDK4 25348397 N/A physical interaction ComPPI
UBTF CCNE1 25348397 N/A physical interaction ComPPI
UBTF ESR1 21182205 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
UBTF CUL7 25348397 N/A physical interaction ComPPI
UBTF OBSL1 25348397 N/A physical interaction ComPPI
UBTF RNF2 25348397 N/A physical interaction ComPPI
UBTF VTI1B 25348397 N/A physical interaction ComPPI
UBTF EDA 25348397 N/A physical interaction ComPPI
UBTF PTGER3 25348397 N/A physical interaction ComPPI
UBTF RTF1 25348397 N/A physical interaction ComPPI
UBTF NTRK1 25348397 N/A physical interaction ComPPI
UBTF IFI16 25348397 N/A physical interaction ComPPI
UBTF EWSR1 25348397 N/A physical interaction ComPPI
UBTF MDM2 25348397 N/A physical interaction ComPPI
UBTF AHSA1 25348397 N/A physical interaction ComPPI
UBTF HNRNPU 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBTF TMPO 25348397 N/A physical interaction ComPPI
UBTF TMPO 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBTF NOP56 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBTF CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBTF MPHOSPH8 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBTF KCNA3 25348397 25829491 27898060 N/A physical interaction ComPPI,OmniPath
UBTF SENP3 25348397 N/A physical interaction ComPPI
UBTF AURKA 25348397 N/A physical interaction ComPPI
UBTF BRCA1 25348397 N/A physical interaction ComPPI
UBTF CDC14B 25348397 N/A physical interaction ComPPI
UBTF PIP4K2A 25348397 N/A physical interaction ComPPI
UBTF CAMKV 25348397 N/A physical interaction ComPPI
UBTF PES1 25348397 N/A physical interaction ComPPI
UBTF MDK 25348397 N/A physical interaction ComPPI
UBTF CPNE7 25348397 N/A physical interaction ComPPI
UBTF NKAPD1 25348397 N/A physical interaction ComPPI
UBTF H1-4 25348397 N/A physical interaction ComPPI
UBTF RSBN1 25348397 N/A physical interaction ComPPI
UBTF KNOP1 25348397 N/A physical interaction ComPPI
UBTF SHPRH 25348397 N/A physical interaction ComPPI
UBTF FOXA1 25348397 N/A physical interaction ComPPI
UBTF TRIM25 25348397 N/A physical interaction ComPPI
UBTF CFTR 25348397 N/A physical interaction ComPPI
UBTF H3C15 25348397 N/A physical interaction ComPPI
UBTF MED19 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UBTF CEBPA 20075868 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation ComPPI,IntAct,OmniPath
UBTF MYC 20195357 21150319 24234451 25348397 association,physical association display technology,tandem affinity purification ComPPI,IntAct
UBTF HEMGN 22712502 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
POLR1A UBTF 25348397 N/A physical interaction ComPPI
TAF1D UBTF 14525934 17318177 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
UBTF UBTF 11592397 14525934 8702533 N/A experimental interaction detection HPRD
EVC UBTF 24234451 30021884 physical association cross-linking study IntAct
SLF1 UBTF 24234451 30021884 physical association cross-linking study IntAct
CDK2 UBTF 10202152 11698641 17287340 18452278 18669648 19007248 19413330 19651622 19691289 20068231 27898060 N/A N/A OmniPath
MAPK3 UBTF 11741541 18669648 19007248 20068231 27898060 inhibition,stimulant N/A OmniPath
CDK4 UBTF 10202152 27898060 N/A N/A OmniPath
MAPK1 UBTF 11741541 18669648 19007248 20068231 27898060 inhibition N/A OmniPath
PHF6 UBTF 23229552 27898060 inhibition N/A OmniPath

Visualization