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GENE：HIC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HIC2
FullNmae HIC ZBTB transcriptional repressor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18595
EnsembleID ENSG00000169635
Uniprot Q96JB3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HIC2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HIC2 GO:0000122,GO:0000978,GO:0001227,GO:0001817,GO:0002682,GO:0003677,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005886,GO:0045892,GO:0046872

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR HIC2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 HIC2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 HIC2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF HIC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HIC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 HIC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR HIC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 HIC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004E008F HIC2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00002152A8 HIC2 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00001799A3 HIC2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE HIC2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000451A1 HIC2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000065D58 HIC2 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F HIC2 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 HIC2 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 HIC2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 HIC2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF HIC2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001919B0 HIC2 20371350 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000753AD HIC2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 HIC2 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000045ED38 HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000027F5F3 HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000759B6A HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000014F13C HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002ED720 HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009262D HIC2 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 HIC2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000015F70F HIC2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001DABC0 HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000036B845 HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D6C3F HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000334286 HIC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002CAE0C HIC2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 HIC2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA HIC2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 HIC2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000521626 HIC2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 HIC2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 HIC2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 HIC2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 HIC2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 HIC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 HIC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 HIC2 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027080C HIC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000610EFA HIC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002971AB HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003CC709 HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002EF20A HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000279B6F HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000192A75 HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D1FC HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000EF0B HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000023F008 HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000015A0D9 HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001012BC HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000209F04 HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E728C HIC2 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDC5L HIC2 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ZBTB8A HIC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LZTS2 HIC2 25348397 N/A physical interaction ComPPI
EHMT2 HIC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
JUN HIC2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CTBP1 HIC2 25348397 N/A physical interaction ComPPI
LIG4 HIC2 25348397 N/A physical interaction ComPPI
E4F1 HIC2 25348397 N/A physical interaction ComPPI
CCNT1 HIC2 12944466 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
PDK2 HIC2 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BARD1 HIC2 25348397 N/A physical interaction ComPPI
HIC2 APP 25348397 N/A physical interaction ComPPI
HIC2 HIC1 11554746 24234451 25348397 27898060 physical association two hybrid,physical interaction ComPPI,IntAct,OmniPath
HIC2 FOXA3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HIC2 FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HIC2 CEP70 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CALU HIC2 25348397 N/A physical interaction ComPPI

Visualization










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