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GENE：MRPL40

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPL40
FullNmae mitochondrial ribosomal protein L40
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14491
EnsembleID ENSG00000185608
Uniprot Q9NQ50

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPL40 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MRPL40 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPL40 GO:0003723,GO:0005515,GO:0005634,GO:0005730,GO:0005739,GO:0005743,GO:0005743,GO:0005761,GO:0005761,GO:0005762,GO:0005762,GO:0009653,GO:0032543

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FOXP3 MRPL40 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 MRPL40 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
E2F4 MRPL40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MRPL40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MRPL40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MRPL40 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYC MRPL40 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA MRPL40 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000040EE1D MRPL40 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C MRPL40 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 MRPL40 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDC5L MRPL40 25348397 N/A physical interaction ComPPI
HNRNPC MRPL40 25348397 N/A physical interaction ComPPI
MRPL28 MRPL40 25348397 N/A physical interaction ComPPI
MRPL40 KRT31 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MRPL40 USP44 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL40 MRPL16 25348397 N/A physical interaction ComPPI
MRPL40 MRPL24 25348397 N/A physical interaction ComPPI
MRPL40 MRPL19 25348397 N/A physical interaction ComPPI
MRPL40 MRPL11 25348397 N/A physical interaction ComPPI
MRPL40 MRPL43 25348397 N/A physical interaction ComPPI
MRPL40 MRPL2 25348397 N/A physical interaction ComPPI
MRPL40 ILF3 25348397 N/A physical interaction ComPPI
MRPL40 DLST 25348397 N/A physical interaction ComPPI
MRPL40 TAP1 25348397 N/A physical interaction ComPPI
MRPL40 TSR1 25348397 N/A physical interaction ComPPI
MRPL40 ZMPSTE24 25348397 N/A physical interaction ComPPI
MRPL40 HNRNPR 25348397 N/A physical interaction ComPPI
MRPL40 SDHB 25348397 N/A physical interaction ComPPI
MRPL40 MMS19 25348397 N/A physical interaction ComPPI
MRPL40 UPF2 25348397 N/A physical interaction ComPPI
MRPL40 CEP57 25348397 N/A physical interaction ComPPI
MRPL40 TRIM27 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MRPL40 TFCP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MRPL40 KRTAP10-3 25348397 N/A physical interaction ComPPI
MRPL40 BTRC 25348397 N/A physical interaction ComPPI
MRPL40 RPL13 25348397 N/A physical interaction ComPPI
MRPL40 RPS8 25348397 N/A physical interaction ComPPI
MRPL40 MRPL4 25348397 N/A physical interaction ComPPI
MRPL40 MRPS30 25348397 N/A physical interaction ComPPI
MRPL40 STK3 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL40 HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
MRPL40 ATL3 25348397 N/A physical interaction ComPPI
MRPL40 EIF3B 25348397 N/A physical interaction ComPPI
MRPL40 HADHA 25348397 N/A physical interaction ComPPI
MRPL40 ATP1A1 25348397 N/A physical interaction ComPPI
MRPL40 ATP5PB 25348397 N/A physical interaction ComPPI
MRPL40 PLRG1 25348397 N/A physical interaction ComPPI
MRPL40 STOML2 25348397 N/A physical interaction ComPPI
MRPL40 PHB2 25348397 N/A physical interaction ComPPI
MRPL40 MRPL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL40 MRPL10 25348397 N/A physical interaction ComPPI
MRPL40 MRPL35 25348397 N/A physical interaction ComPPI
MRPL40 FGF8 25348397 N/A physical interaction ComPPI
MRPL40 MRPL12 25348397 N/A physical interaction ComPPI
MRPL40 SLC25A10 25348397 N/A physical interaction ComPPI
MRPL40 AURKAIP1 25348397 N/A physical interaction ComPPI
MRPL40 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MRPL40 YBX1 22118625 24234451 25348397 association tandem affinity purification ComPPI,IntAct
MRPL40 SLC25A5 23260140 24234451 25348397 association blue native page ComPPI,IntAct
MRPL40 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
MRPL40 PDK1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPL40 TRMT61B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPL15 MRPL40 25348397 N/A physical interaction ComPPI

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