GENE：NREP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | NREP |
| FullNmae | neuronal regeneration related protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16834 |
| EnsembleID | ENSG00000134986 |
| Uniprot | Q16612 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| NREP | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| NREP | GO:0005515,GO:0005737,GO:0017015,GO:0031103,GO:0045664 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | NREP | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | NREP | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| HIF1A | NREP | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| FOXP3 | NREP | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | NREP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000F31F4 | NREP | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | NREP | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000122ED0 | NREP | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000045DBD | NREP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ACA7C | NREP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BD1DE | NREP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039D790 | NREP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| EEF1A1 | NREP | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| EIF6 | NREP | 22365962 24234451 25348397 27898060 | colocalization,physical association | anti bait coimmunoprecipitation,two hybrid,coimmunoprecipitation,fluorescence microscopy,confocal microscopy | ComPPI,IntAct,OmniPath |
| ATM | NREP | 24234451 25348397 25640309 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| MAGED1 | NREP | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | NREP | 25348397 | N/A | physical interaction | ComPPI |
| KMT2B | NREP | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| IGSF21 | NREP | 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
| NREP | EEF1A1P5 | 25348397 | N/A | physical interaction | ComPPI |
| PRKCE | NREP | 16229809 27898060 | N/A | N/A | OmniPath |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009B75B6 | NREP | 27087310 | direct interaction,inhibition | N/A | NPInter |