Gene Information gene info

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GENE：SHISA5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SHISA5
FullNmae shisa family member 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30376
EnsembleID ENSG00000164054
Uniprot Q8N114

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SHISA5 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SHISA5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SHISA5 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SHISA5 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SHISA5 GO:0005515,GO:0005783,GO:0005788,GO:0005789,GO:0031965,GO:0042771,GO:0043123

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SHISA5 hsa:51246 path:hsa04115 p53 signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 SHISA5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C SHISA5 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF SHISA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SHISA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SHISA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SHISA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SHISA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR SHISA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SHISA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000002103A SHISA5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D SHISA5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000246356 SHISA5 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TP53 SHISA5 25361965 interaction type N/A PTMCode2
SHISA5 TP53 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
COPS5 SHISA5 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WWOX SHISA5 15064722 24234451 25348397 physical association far western blotting,protein array ComPPI,IntAct
SHISA5 ALG2 17889823 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SHISA5 HNRNPD 25348397 N/A physical interaction ComPPI
SHISA5 TFAP2C 24234451 24835590 25348397 physical association two hybrid ComPPI,IntAct
SHISA5 TP53 12135983 14525934 N/A experimental interaction detection HPRD

Source Target Pmid Interactiontype Methods Database
URS00008B4B0E SHISA5 27087310 direct interaction,inhibition N/A NPInter

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